Treg cells-derived exosomes promote blood-spinal cord barrier repair and motor function recovery after spinal cord injury by delivering miR-2861

Treg cells-derived exosomes promote blood-spinal cord barrier repair and motor function recovery after spinal cord injury by delivering miR-2861

Abstract The blood-spinal cord barrier (BSCB) is a physical barrier between the blood and the spinal cord parenchyma. Current evidence suggests that the disruption of BSCB integrity after spinal cord injury can lead to secondary injuries such as spinal cord edema and excessive inflammatory response....

Full description

Bibliographic Details
Main Authors: Guang Kong, Wu Xiong, Cong Li, Chenyu Xiao, Siming Wang, Wenbo Li, Xiangjun Chen, Juan Wang, Sheng Chen, Yongjie Zhang, Jun Gu, Jin Fan, Zhengshuai Jin
Format: Article
Language:English
Published: BMC 2023-10-01
Series:Journal of Nanobiotechnology
Subjects:
Spinal cord injury
Regulatory T cells
Blood-spinal cord barrier
Exosomes
miRNA
Online Access:https://doi.org/10.1186/s12951-023-02089-6

Similar Items

Similar Items