A novel proteomic signature of osteoclast differentiation unveils the deubiquitinase UCHL1 as a necessary osteoclastogenic driver
Abstract Bone destruction, a major source of morbidity, is mediated by heightened differentiation and activity of osteoclasts (OC), highly specialized multinucleated myeloid cells endowed with unique bone-resorptive capacity. The molecular mechanisms regulating OC differentiation in the bone marrow...
| Prif Awduron: | , , , , , , , , |
|---|---|
| Fformat: | Erthygl |
| Iaith: | English |
| Cyhoeddwyd: |
Nature Portfolio
2024-03-01
|
| Cyfres: | Scientific Reports |
| Mynediad Ar-lein: | https://doi.org/10.1038/s41598-024-57898-y |