Role of the tumor microenvironment in malignant melanoma organoids during the development and metastasis of tumors

Malignant melanoma (MM) is the most metastatic and aggressive form of skin cancer, and carries a high risk of death. Immune-checkpoint inhibitor therapy and molecular-targeted therapy can prolong the survival of patients with advanced MM significantly. However, the low response rate and inevitable d...

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Bibliographic Details
Main Authors: Siyu Zhou, Jinghan Lu, Shiyang Liu, Jiaqi Shao, Zhanwei Liu, Jianjun Li, Wan’an Xiao
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2023.1166916/full