Epidemiology and clinical features of cutaneous leishmaniasis in Khyber Pakhtunkhwa, Pakistan
Abstract Current cross-sectional study was carried out between September 2019 to January 2020 at the Department of Pathology, Mardan Medical Complex (MMC), Mardan, and District Headquarter Hospital North Waziristan, Khyber Pakhtunkhwa (KP), Pakistan. The objectives of the current study were to deter...
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| Format: | Article |
| Language: | English |
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Instituto Internacional de Ecologia
2022-08-01
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| Series: | Brazilian Journal of Biology |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1519-69842024000100371&tlng=en |
| _version_ | 1828152006550749184 |
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| author | W. Iqbal U. Iram S. Nisar N. Musa A. Alam M. R. Khan B. Ullah M. Ullah I. Ali |
| author_facet | W. Iqbal U. Iram S. Nisar N. Musa A. Alam M. R. Khan B. Ullah M. Ullah I. Ali |
| author_sort | W. Iqbal |
| collection | DOAJ |
| description | Abstract Current cross-sectional study was carried out between September 2019 to January 2020 at the Department of Pathology, Mardan Medical Complex (MMC), Mardan, and District Headquarter Hospital North Waziristan, Khyber Pakhtunkhwa (KP), Pakistan. The objectives of the current study were to determine the prevalence of leishmaniasis and its associated risk factors in selected districts of KP province, Pakistan. Altogether, three hundred and seventy-four (n=374) leishmaniosis patients were included in the current study. Skin specimen from the ulcer border were collected. The slides were stained by Giemsa stain and examined for the presence of amastigote. The prevalence of leishmania infected patients in different region of KP were as follows: North Waziristan region 53.7 (n=201) District Mardan 34.7% (n=130); District Nowshera 6.7% (n=25), District Swabi 1.1% (n=4) and other Districts i.e. Dir, Malakand, Buner and Bajawarr were 3.7% (n=14). The frequency of leishmaniasis were more in male and majority of the infected patients were in the age group of <10 years. Among n=374 patients 95.7% (n= 358) had cutaneous leishmaniasis while 3% (n= 11) had mucocutaneous type of infection and 1.3% (n= 5) patients had both cutaneous and mucocutaneous infection. Upon treatment by Sodium stibogluconate (SSG) 97% (n=362) showed clinical signs of complete or partial recovery of their skin lesions. Conclusively, highest incidence of leishmania infection occurred during short study period and majority of the cases showed positive response to treatment. |
| first_indexed | 2024-04-11T22:06:40Z |
| format | Article |
| id | doaj.art-eda515ef21c84779ba2028caeb1a7cc9 |
| institution | Directory Open Access Journal |
| issn | 1678-4375 |
| language | English |
| last_indexed | 2024-04-11T22:06:40Z |
| publishDate | 2022-08-01 |
| publisher | Instituto Internacional de Ecologia |
| record_format | Article |
| series | Brazilian Journal of Biology |
| spelling | doaj.art-eda515ef21c84779ba2028caeb1a7cc92022-12-22T04:00:43ZengInstituto Internacional de EcologiaBrazilian Journal of Biology1678-43752022-08-018410.1590/1519-6984.249124Epidemiology and clinical features of cutaneous leishmaniasis in Khyber Pakhtunkhwa, PakistanW. IqbalU. IramS. NisarN. MusaA. AlamM. R. KhanB. UllahM. UllahI. Alihttps://orcid.org/0000-0002-6346-705XAbstract Current cross-sectional study was carried out between September 2019 to January 2020 at the Department of Pathology, Mardan Medical Complex (MMC), Mardan, and District Headquarter Hospital North Waziristan, Khyber Pakhtunkhwa (KP), Pakistan. The objectives of the current study were to determine the prevalence of leishmaniasis and its associated risk factors in selected districts of KP province, Pakistan. Altogether, three hundred and seventy-four (n=374) leishmaniosis patients were included in the current study. Skin specimen from the ulcer border were collected. The slides were stained by Giemsa stain and examined for the presence of amastigote. The prevalence of leishmania infected patients in different region of KP were as follows: North Waziristan region 53.7 (n=201) District Mardan 34.7% (n=130); District Nowshera 6.7% (n=25), District Swabi 1.1% (n=4) and other Districts i.e. Dir, Malakand, Buner and Bajawarr were 3.7% (n=14). The frequency of leishmaniasis were more in male and majority of the infected patients were in the age group of <10 years. Among n=374 patients 95.7% (n= 358) had cutaneous leishmaniasis while 3% (n= 11) had mucocutaneous type of infection and 1.3% (n= 5) patients had both cutaneous and mucocutaneous infection. Upon treatment by Sodium stibogluconate (SSG) 97% (n=362) showed clinical signs of complete or partial recovery of their skin lesions. Conclusively, highest incidence of leishmania infection occurred during short study period and majority of the cases showed positive response to treatment.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1519-69842024000100371&tlng=encutaneous leishmaniasismucocutaneus leishmaniasistreatmentKPPakistan |
| spellingShingle | W. Iqbal U. Iram S. Nisar N. Musa A. Alam M. R. Khan B. Ullah M. Ullah I. Ali Epidemiology and clinical features of cutaneous leishmaniasis in Khyber Pakhtunkhwa, Pakistan Brazilian Journal of Biology cutaneous leishmaniasis mucocutaneus leishmaniasis treatment KP Pakistan |
| title | Epidemiology and clinical features of cutaneous leishmaniasis in Khyber Pakhtunkhwa, Pakistan |
| title_full | Epidemiology and clinical features of cutaneous leishmaniasis in Khyber Pakhtunkhwa, Pakistan |
| title_fullStr | Epidemiology and clinical features of cutaneous leishmaniasis in Khyber Pakhtunkhwa, Pakistan |
| title_full_unstemmed | Epidemiology and clinical features of cutaneous leishmaniasis in Khyber Pakhtunkhwa, Pakistan |
| title_short | Epidemiology and clinical features of cutaneous leishmaniasis in Khyber Pakhtunkhwa, Pakistan |
| title_sort | epidemiology and clinical features of cutaneous leishmaniasis in khyber pakhtunkhwa pakistan |
| topic | cutaneous leishmaniasis mucocutaneus leishmaniasis treatment KP Pakistan |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1519-69842024000100371&tlng=en |
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