Interaction between daidzein and hesperetin on antispasmodic action in isolated sensitized and non-sensitized guinea-pig tracheas

Interaction between daidzein and hesperetin on antispasmodic action in isolated sensitized and non-sensitized guinea-pig tracheas

In traditional Chinese medicine (TCM), a combination of kudzu and Chen-Pi is frequently prescribed for relieving colds, fever, bronchitis and cough. It contains daidzein and hesperetin, selective inhibitors of family 3 (PDE3) and 4 (PDE4) of phosphodiesterases (PDEs), respectively. In passively sens...

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Bibliographic Details
Main Authors: Chung-Hung eShih, Tsu-Ya eChang, Wun-Chang eKo
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-03-01
Series:Frontiers in Pharmacology
Subjects:
guinea-pig trachea
Synergism
Antagonism
daidzein
hesperetin
Isobole
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2016.00075/full

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