Case Report: Use of PET/CT to Guide Treatment in a Cat With Presentation Consistent With Hodgkin's-Like Lymphoma
An 8-year-old male neutered Domestic Long Hair cat was presented for a cervical swelling that was suspected to be an enlarged left retropharyngeal lymph node. In the absence of other lymphadenopathy, this was initially suspected to be Hodgkin's-like lymphoma. A positron emission tomography–comp...
| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2021-04-01
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| Series: | Frontiers in Veterinary Science |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fvets.2021.619264/full |
| _version_ | 1818937000233795584 |
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| author | Carolyn L. Chen Matthew R. Cook Megan E. Brown Sarah Lumbrezer-Johnson Eric T. Hostnik Janis M. Lapsley Phillip Lerche Vincent A. Wavreille Maria I. Menendez Michael V. Knopp Sarah C. Linn Christopher Premanandan Laura E. Selmic |
| author_facet | Carolyn L. Chen Matthew R. Cook Megan E. Brown Sarah Lumbrezer-Johnson Eric T. Hostnik Janis M. Lapsley Phillip Lerche Vincent A. Wavreille Maria I. Menendez Michael V. Knopp Sarah C. Linn Christopher Premanandan Laura E. Selmic |
| author_sort | Carolyn L. Chen |
| collection | DOAJ |
| description | An 8-year-old male neutered Domestic Long Hair cat was presented for a cervical swelling that was suspected to be an enlarged left retropharyngeal lymph node. In the absence of other lymphadenopathy, this was initially suspected to be Hodgkin's-like lymphoma. A positron emission tomography–computed tomography (PET/CT) scan was performed using 2-deoxy-2-[18F]-fluorodeoxyglucose (18F-FDG) to assess for evidence of disease in other locations to guide treatment. Multifocal increased radiopharmaceutical uptake was identified, indicating disease in multiple organs. High-grade lymphoma was confirmed on tissue biopsy. As such, systemic cytotoxic chemotherapy was recommended instead of lymph node extirpation surgery. The cat received a modified CHOP chemotherapy protocol and attained a temporary partial remission. After 2 months of treatment, the cat stopped responding to chemotherapy and was eventually euthanized due to a relapse of disease and decreased quality of life. This case describes the utility of PET/CT to guide treatment in a cat with a presentation consistent with Hodgkin's-like lymphoma. |
| first_indexed | 2024-12-20T05:45:00Z |
| format | Article |
| id | doaj.art-edac2f3cc9c94541934a893d840b56ee |
| institution | Directory Open Access Journal |
| issn | 2297-1769 |
| language | English |
| last_indexed | 2024-12-20T05:45:00Z |
| publishDate | 2021-04-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Veterinary Science |
| spelling | doaj.art-edac2f3cc9c94541934a893d840b56ee2022-12-21T19:51:21ZengFrontiers Media S.A.Frontiers in Veterinary Science2297-17692021-04-01810.3389/fvets.2021.619264619264Case Report: Use of PET/CT to Guide Treatment in a Cat With Presentation Consistent With Hodgkin's-Like LymphomaCarolyn L. Chen0Matthew R. Cook1Megan E. Brown2Sarah Lumbrezer-Johnson3Eric T. Hostnik4Janis M. Lapsley5Phillip Lerche6Vincent A. Wavreille7Maria I. Menendez8Michael V. Knopp9Sarah C. Linn10Christopher Premanandan11Laura E. Selmic12Veterinary Medical Center, The Ohio State University, Columbus, OH, United StatesVeterinary Medical Center, The Ohio State University, Columbus, OH, United StatesVeterinary Medical Center, The Ohio State University, Columbus, OH, United StatesVeterinary Medical Center, The Ohio State University, Columbus, OH, United StatesVeterinary Medical Center, The Ohio State University, Columbus, OH, United StatesVeterinary Medical Center, The Ohio State University, Columbus, OH, United StatesVeterinary Medical Center, The Ohio State University, Columbus, OH, United StatesDepartment of Surgery, University of Zurich, Zurich, SwitzerlandDepartment of Radiology, The Wright Center of Innovation in Biomedical Imaging, The Ohio State University Wexner Medical Center, Columbus, OH, United StatesDepartment of Radiology, The Wright Center of Innovation in Biomedical Imaging, The Ohio State University Wexner Medical Center, Columbus, OH, United StatesDepartment of Veterinary Biosciences, The Ohio State University, Columbus, OH, United StatesDepartment of Veterinary Biosciences, The Ohio State University, Columbus, OH, United StatesVeterinary Medical Center, The Ohio State University, Columbus, OH, United StatesAn 8-year-old male neutered Domestic Long Hair cat was presented for a cervical swelling that was suspected to be an enlarged left retropharyngeal lymph node. In the absence of other lymphadenopathy, this was initially suspected to be Hodgkin's-like lymphoma. A positron emission tomography–computed tomography (PET/CT) scan was performed using 2-deoxy-2-[18F]-fluorodeoxyglucose (18F-FDG) to assess for evidence of disease in other locations to guide treatment. Multifocal increased radiopharmaceutical uptake was identified, indicating disease in multiple organs. High-grade lymphoma was confirmed on tissue biopsy. As such, systemic cytotoxic chemotherapy was recommended instead of lymph node extirpation surgery. The cat received a modified CHOP chemotherapy protocol and attained a temporary partial remission. After 2 months of treatment, the cat stopped responding to chemotherapy and was eventually euthanized due to a relapse of disease and decreased quality of life. This case describes the utility of PET/CT to guide treatment in a cat with a presentation consistent with Hodgkin's-like lymphoma.https://www.frontiersin.org/articles/10.3389/fvets.2021.619264/fullHodgkin'slymphomaPET/CTchemotherapyfluorodeoxiglucose F18lymphadenopathy |
| spellingShingle | Carolyn L. Chen Matthew R. Cook Megan E. Brown Sarah Lumbrezer-Johnson Eric T. Hostnik Janis M. Lapsley Phillip Lerche Vincent A. Wavreille Maria I. Menendez Michael V. Knopp Sarah C. Linn Christopher Premanandan Laura E. Selmic Case Report: Use of PET/CT to Guide Treatment in a Cat With Presentation Consistent With Hodgkin's-Like Lymphoma Frontiers in Veterinary Science Hodgkin's lymphoma PET/CT chemotherapy fluorodeoxiglucose F18 lymphadenopathy |
| title | Case Report: Use of PET/CT to Guide Treatment in a Cat With Presentation Consistent With Hodgkin's-Like Lymphoma |
| title_full | Case Report: Use of PET/CT to Guide Treatment in a Cat With Presentation Consistent With Hodgkin's-Like Lymphoma |
| title_fullStr | Case Report: Use of PET/CT to Guide Treatment in a Cat With Presentation Consistent With Hodgkin's-Like Lymphoma |
| title_full_unstemmed | Case Report: Use of PET/CT to Guide Treatment in a Cat With Presentation Consistent With Hodgkin's-Like Lymphoma |
| title_short | Case Report: Use of PET/CT to Guide Treatment in a Cat With Presentation Consistent With Hodgkin's-Like Lymphoma |
| title_sort | case report use of pet ct to guide treatment in a cat with presentation consistent with hodgkin s like lymphoma |
| topic | Hodgkin's lymphoma PET/CT chemotherapy fluorodeoxiglucose F18 lymphadenopathy |
| url | https://www.frontiersin.org/articles/10.3389/fvets.2021.619264/full |
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