Pathogenicity and Viral Shedding of MERS-CoV in Immunocompromised Rhesus Macaques

Pathogenicity and Viral Shedding of MERS-CoV in Immunocompromised Rhesus Macaques

Middle East respiratory syndrome coronavirus (MERS-CoV) has recently emerged in the Middle East. Since 2012, there have been approximately 2,100 confirmed cases, with a 35% case fatality rate. Disease severity has been linked to patient health status, as people with chronic diseases or an immunocomp...

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Bibliographic Details
Main Authors: Joseph Prescott, Darryl Falzarano, Emmie de Wit, Kath Hardcastle, Friederike Feldmann, Elaine Haddock, Dana Scott, Heinz Feldmann, Vincent Jacobus Munster
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-02-01
Series:Frontiers in Immunology
Subjects:
Middle East respiratory syndrome coronavirus
immunosuppression
pathology
shedding
macaque monkey
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00205/full

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