Chemo-Enzymatic Strategy for the Efficient Synthesis of Steroidal Drugs with 10α-Methyl Group and a Side Chain at C17-Position from Biorenewable Phytosterols
| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
American Chemical Society
2024-03-01
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| Series: | JACS Au |
| Online Access: | https://doi.org/10.1021/jacsau.3c00688 |
| _version_ | 1797198610321899520 |
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| author | Xuemei Li Rui Zhang Jianjiong Li Na Liu Xi Chen Yiyin Liu Gang Zhao Kai Ding Peiyuan Yao Jinhui Feng Qiaqing Wu Dunming Zhu Yanhe Ma |
| author_facet | Xuemei Li Rui Zhang Jianjiong Li Na Liu Xi Chen Yiyin Liu Gang Zhao Kai Ding Peiyuan Yao Jinhui Feng Qiaqing Wu Dunming Zhu Yanhe Ma |
| author_sort | Xuemei Li |
| collection | DOAJ |
| first_indexed | 2024-04-24T07:02:36Z |
| format | Article |
| id | doaj.art-edb6585b3c384e4a9cbb7aaa84346eaf |
| institution | Directory Open Access Journal |
| issn | 2691-3704 |
| language | English |
| last_indexed | 2024-04-24T07:02:36Z |
| publishDate | 2024-03-01 |
| publisher | American Chemical Society |
| record_format | Article |
| series | JACS Au |
| spelling | doaj.art-edb6585b3c384e4a9cbb7aaa84346eaf2024-04-22T07:42:01ZengAmerican Chemical SocietyJACS Au2691-37042024-03-01441356136410.1021/jacsau.3c00688Chemo-Enzymatic Strategy for the Efficient Synthesis of Steroidal Drugs with 10α-Methyl Group and a Side Chain at C17-Position from Biorenewable PhytosterolsXuemei Li0Rui Zhang1Jianjiong Li2Na Liu3Xi Chen4Yiyin Liu5Gang Zhao6Kai Ding7Peiyuan Yao8Jinhui Feng9Qiaqing Wu10Dunming Zhu11Yanhe Ma12National Engineering Research Center of Industrial Enzymes and Tianjin Engineering Research Center of Biocatalytic Technology, Key Laboratory of Engineering Biology for Low-carbon Manufacturing, National Center of Technology Innovation for Synthetic Biology, and Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, ChinaNational Engineering Research Center of Industrial Enzymes and Tianjin Engineering Research Center of Biocatalytic Technology, Key Laboratory of Engineering Biology for Low-carbon Manufacturing, National Center of Technology Innovation for Synthetic Biology, and Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, ChinaNational Engineering Research Center of Industrial Enzymes and Tianjin Engineering Research Center of Biocatalytic Technology, Key Laboratory of Engineering Biology for Low-carbon Manufacturing, National Center of Technology Innovation for Synthetic Biology, and Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, ChinaNational Engineering Research Center of Industrial Enzymes and Tianjin Engineering Research Center of Biocatalytic Technology, Key Laboratory of Engineering Biology for Low-carbon Manufacturing, National Center of Technology Innovation for Synthetic Biology, and Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, ChinaNational Engineering Research Center of Industrial Enzymes and Tianjin Engineering Research Center of Biocatalytic Technology, Key Laboratory of Engineering Biology for Low-carbon Manufacturing, National Center of Technology Innovation for Synthetic Biology, and Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, ChinaNational Engineering Research Center of Industrial Enzymes and Tianjin Engineering Research Center of Biocatalytic Technology, Key Laboratory of Engineering Biology for Low-carbon Manufacturing, National Center of Technology Innovation for Synthetic Biology, and Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, ChinaCAS Key Laboratory of Synthetic Chemistry of Natural Substances, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, ChinaCAS Key Laboratory of Synthetic Chemistry of Natural Substances, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, ChinaNational Engineering Research Center of Industrial Enzymes and Tianjin Engineering Research Center of Biocatalytic Technology, Key Laboratory of Engineering Biology for Low-carbon Manufacturing, National Center of Technology Innovation for Synthetic Biology, and Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, ChinaNational Engineering Research Center of Industrial Enzymes and Tianjin Engineering Research Center of Biocatalytic Technology, Key Laboratory of Engineering Biology for Low-carbon Manufacturing, National Center of Technology Innovation for Synthetic Biology, and Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, ChinaNational Engineering Research Center of Industrial Enzymes and Tianjin Engineering Research Center of Biocatalytic Technology, Key Laboratory of Engineering Biology for Low-carbon Manufacturing, National Center of Technology Innovation for Synthetic Biology, and Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, ChinaNational Engineering Research Center of Industrial Enzymes and Tianjin Engineering Research Center of Biocatalytic Technology, Key Laboratory of Engineering Biology for Low-carbon Manufacturing, National Center of Technology Innovation for Synthetic Biology, and Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, ChinaNational Engineering Research Center of Industrial Enzymes and Tianjin Engineering Research Center of Biocatalytic Technology, Key Laboratory of Engineering Biology for Low-carbon Manufacturing, National Center of Technology Innovation for Synthetic Biology, and Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, Chinahttps://doi.org/10.1021/jacsau.3c00688 |
| spellingShingle | Xuemei Li Rui Zhang Jianjiong Li Na Liu Xi Chen Yiyin Liu Gang Zhao Kai Ding Peiyuan Yao Jinhui Feng Qiaqing Wu Dunming Zhu Yanhe Ma Chemo-Enzymatic Strategy for the Efficient Synthesis of Steroidal Drugs with 10α-Methyl Group and a Side Chain at C17-Position from Biorenewable Phytosterols JACS Au |
| title | Chemo-Enzymatic Strategy for the Efficient Synthesis of Steroidal Drugs with 10α-Methyl Group and a Side Chain at C17-Position from Biorenewable Phytosterols |
| title_full | Chemo-Enzymatic Strategy for the Efficient Synthesis of Steroidal Drugs with 10α-Methyl Group and a Side Chain at C17-Position from Biorenewable Phytosterols |
| title_fullStr | Chemo-Enzymatic Strategy for the Efficient Synthesis of Steroidal Drugs with 10α-Methyl Group and a Side Chain at C17-Position from Biorenewable Phytosterols |
| title_full_unstemmed | Chemo-Enzymatic Strategy for the Efficient Synthesis of Steroidal Drugs with 10α-Methyl Group and a Side Chain at C17-Position from Biorenewable Phytosterols |
| title_short | Chemo-Enzymatic Strategy for the Efficient Synthesis of Steroidal Drugs with 10α-Methyl Group and a Side Chain at C17-Position from Biorenewable Phytosterols |
| title_sort | chemo enzymatic strategy for the efficient synthesis of steroidal drugs with 10α methyl group and a side chain at c17 position from biorenewable phytosterols |
| url | https://doi.org/10.1021/jacsau.3c00688 |
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