Biocatalytic Cascade of Sebacic Acid Production with In Situ Co-Factor Regeneration Enabled by Engineering of an Alcohol Dehydrogenase

Biocatalytic Cascade of Sebacic Acid Production with In Situ Co-Factor Regeneration Enabled by Engineering of an Alcohol Dehydrogenase

Sebacic acid (1,10-decanedioic acid) is an important chemical intermediate. Traditional chemical oxidation methods for sebacic acid production do not conform with “green” manufacturing. With the rapid development of enzymatic technologies, a biocatalytic cascade method based on the Baeyer–Villiger m...

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Bibliographic Details
Main Authors: Jie Lu, Dong Lu, Qiuyang Wu, Shuming Jin, Junfeng Liu, Meng Qin, Li Deng, Fang Wang, Kaili Nie
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Catalysts
Subjects:
co-factor regeneration
alcohol dehydrogenase
sebacic acid
enzymatic cascade reaction
in silico simulation
Online Access:https://www.mdpi.com/2073-4344/12/11/1318

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