Anticancer Potential of Resveratrol, β-Lapachone and Their Analogues
This review aims to explore the potential of resveratrol, a polyphenol stilbene, and beta-lapachone, a naphthoquinone, as well as their derivatives, in the development of new drug candidates for cancer. A brief history of these compounds is reviewed along with their potential effects and mechanisms...
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-02-01
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| Series: | Molecules |
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| Online Access: | https://www.mdpi.com/1420-3049/25/4/893 |
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| author | Danielly C. Ferraz da Costa Luciana Pereira Rangel Mafalda Maria Duarte da Cunha Martins-Dinis Giulia Diniz da Silva Ferretti Vitor F. Ferreira Jerson L. Silva |
| author_facet | Danielly C. Ferraz da Costa Luciana Pereira Rangel Mafalda Maria Duarte da Cunha Martins-Dinis Giulia Diniz da Silva Ferretti Vitor F. Ferreira Jerson L. Silva |
| author_sort | Danielly C. Ferraz da Costa |
| collection | DOAJ |
| description | This review aims to explore the potential of resveratrol, a polyphenol stilbene, and beta-lapachone, a naphthoquinone, as well as their derivatives, in the development of new drug candidates for cancer. A brief history of these compounds is reviewed along with their potential effects and mechanisms of action and the most recent attempts to improve their bioavailability and potency against different types of cancer. |
| first_indexed | 2024-12-13T03:01:00Z |
| format | Article |
| id | doaj.art-edb83b2b4597416e81eb5a8087335a32 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-12-13T03:01:00Z |
| publishDate | 2020-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-edb83b2b4597416e81eb5a8087335a322022-12-22T00:01:51ZengMDPI AGMolecules1420-30492020-02-0125489310.3390/molecules25040893molecules25040893Anticancer Potential of Resveratrol, β-Lapachone and Their AnaloguesDanielly C. Ferraz da Costa0Luciana Pereira Rangel1Mafalda Maria Duarte da Cunha Martins-Dinis2Giulia Diniz da Silva Ferretti3Vitor F. Ferreira4Jerson L. Silva5Departamento de Nutrição Básica e Experimental, Instituto de Nutrição, Universidade do Estado do Rio de Janeiro, Rio de Janeiro 20550-013, BrazilFaculdade de Farmácia, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941-902, BrazilPrograma de Biologia Estrutural, Instituto de Bioquímica Médica Leopoldo de Meis, Instituto Nacional de Ciência e Tecnologia de Biologia Estrutural e Bioimagem, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941-902, BrazilPrograma de Biologia Estrutural, Instituto de Bioquímica Médica Leopoldo de Meis, Instituto Nacional de Ciência e Tecnologia de Biologia Estrutural e Bioimagem, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941-902, BrazilDepartamento de Tecnologia Farmacêutica, Faculdade de Farmácia, Universidade Federal Fluminense, Rio de Janeiro 24241-000, BrazilPrograma de Biologia Estrutural, Instituto de Bioquímica Médica Leopoldo de Meis, Instituto Nacional de Ciência e Tecnologia de Biologia Estrutural e Bioimagem, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941-902, BrazilThis review aims to explore the potential of resveratrol, a polyphenol stilbene, and beta-lapachone, a naphthoquinone, as well as their derivatives, in the development of new drug candidates for cancer. A brief history of these compounds is reviewed along with their potential effects and mechanisms of action and the most recent attempts to improve their bioavailability and potency against different types of cancer.https://www.mdpi.com/1420-3049/25/4/893resveratrolβ-lapachonecancer |
| spellingShingle | Danielly C. Ferraz da Costa Luciana Pereira Rangel Mafalda Maria Duarte da Cunha Martins-Dinis Giulia Diniz da Silva Ferretti Vitor F. Ferreira Jerson L. Silva Anticancer Potential of Resveratrol, β-Lapachone and Their Analogues Molecules resveratrol β-lapachone cancer |
| title | Anticancer Potential of Resveratrol, β-Lapachone and Their Analogues |
| title_full | Anticancer Potential of Resveratrol, β-Lapachone and Their Analogues |
| title_fullStr | Anticancer Potential of Resveratrol, β-Lapachone and Their Analogues |
| title_full_unstemmed | Anticancer Potential of Resveratrol, β-Lapachone and Their Analogues |
| title_short | Anticancer Potential of Resveratrol, β-Lapachone and Their Analogues |
| title_sort | anticancer potential of resveratrol β lapachone and their analogues |
| topic | resveratrol β-lapachone cancer |
| url | https://www.mdpi.com/1420-3049/25/4/893 |
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