Enhanced triacylglycerol production in the diatom Phaeodactylum tricornutum by inactivation of a Hotdog-fold thioesterase gene using TALEN-based targeted mutagenesis

Enhanced triacylglycerol production in the diatom Phaeodactylum tricornutum by inactivation of a Hotdog-fold thioesterase gene using TALEN-based targeted mutagenesis

Abstract Background In photosynthetic oleaginous microalgae, acyl-CoA molecules are used as substrates for the biosynthesis of membrane glycerolipids, triacylglycerol (TAG) and other acylated molecules. Acyl-CoA can also be directed to beta-oxidative catabolism. They can be utilized by a number of l...

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Bibliographic Details
Main Authors: Xiahui Hao, Ling Luo, Juliette Jouhet, Fabrice Rébeillé, Eric Maréchal, Hanhua Hu, Yufang Pan, Xiaoming Tan, Zhuo Chen, Lingjie You, Hong Chen, Fang Wei, Yangmin Gong
Format: Article
Language:English
Published: BMC 2018-11-01
Series:Biotechnology for Biofuels
Subjects:
Acyl-CoA thioesterase
Acyl-CoA
Fatty acids
Phaeodactylum tricornutum
TALEN
Triacylglycerols
Online Access:http://link.springer.com/article/10.1186/s13068-018-1309-3

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