Surgical outcomes and factors associated with postoperative complications of colorectal cancer in a Colombian Caribbean population: Results from a regional referral hospital
Abstract Introduction Colorectal cancer is the most common malignant neoplasm of the gastrointestinal tract. Its incidence and mortality vary markedly at a global level. Assessing the epidemiological behavior of this condition allows reevaluating diagnostic, therapeutic and prognostic options, based...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2023-04-01
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| Series: | Cancer Reports |
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| Online Access: | https://doi.org/10.1002/cnr2.1766 |
| _version_ | 1797851543148429312 |
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| author | Edgar Ernesto Vergara Dagobeth Gian Alberto Núñez Rojas Juan Carlos Hoyos Valdelamar Ivan David Lozada‐Martínez Amileth Suarez Causado Alexis Rafael Narvaez‐Rojas |
| author_facet | Edgar Ernesto Vergara Dagobeth Gian Alberto Núñez Rojas Juan Carlos Hoyos Valdelamar Ivan David Lozada‐Martínez Amileth Suarez Causado Alexis Rafael Narvaez‐Rojas |
| author_sort | Edgar Ernesto Vergara Dagobeth |
| collection | DOAJ |
| description | Abstract Introduction Colorectal cancer is the most common malignant neoplasm of the gastrointestinal tract. Its incidence and mortality vary markedly at a global level. Assessing the epidemiological behavior of this condition allows reevaluating diagnostic, therapeutic and prognostic options, based on new findings. In Colombia, few studies have correlated variables associated with surgical and oncological outcomes in this type of cancer. Then, the aim of this study was to evaluate the surgical outcomes and factors associated with postoperative complications of colorectal cancer in a Colombian Caribbean Population. Methods Retrospective cross‐sectional study, including patients with a histopathological diagnosis of colorectal cancer who underwent open or laparoscopic surgery, during a period of two years (2018–2020), from a regional referral hospital. Clinical history variables were collected. Frequencies and prevalence ratios were calculated. Results A total of 84 patients were finally included. Adenocarcinoma of non‐special type with advanced clinical stages was the most prevalent (72.6%). Rectal neoplasia (45.2%) was the most frequent anatomical subsite, followed by proximal colon (p = 0.026). The anatomical subsite of the neoplasm, intraoperative complication (PR 1.38; 95% CI, 1.21–1.59, p = 0.001) and intensive care stay (PR 1.062; 95% CI, 1.01–1.12, p = 0.048) were associated with postoperative outcome. Conclusions The anatomical subsite of the neoplasm location, the presence of intraoperative complications and the stay in intensive care may be associated with the surgical and oncological outcome of individuals with colon cancer from the Colombian Caribbean region. |
| first_indexed | 2024-04-09T19:19:33Z |
| format | Article |
| id | doaj.art-edc07a9310d24f899597b1b0f3acef81 |
| institution | Directory Open Access Journal |
| issn | 2573-8348 |
| language | English |
| last_indexed | 2024-04-09T19:19:33Z |
| publishDate | 2023-04-01 |
| publisher | Wiley |
| record_format | Article |
| series | Cancer Reports |
| spelling | doaj.art-edc07a9310d24f899597b1b0f3acef812023-04-05T16:17:18ZengWileyCancer Reports2573-83482023-04-0164n/an/a10.1002/cnr2.1766Surgical outcomes and factors associated with postoperative complications of colorectal cancer in a Colombian Caribbean population: Results from a regional referral hospitalEdgar Ernesto Vergara Dagobeth0Gian Alberto Núñez Rojas1Juan Carlos Hoyos Valdelamar2Ivan David Lozada‐Martínez3Amileth Suarez Causado4Alexis Rafael Narvaez‐Rojas5School of Medicine Universidad de Sucre Sincelejo ColombiaDepartment of Surgery, School of Medicine Universidad de Cartagena Cartagena ColombiaDepartment of Surgery, School of Medicine Universidad de Cartagena Cartagena ColombiaGrupo Prometeus y Biomedicina Aplicada a las Ciencias Clínicas School of Medicine, Universidad de Cartagena Cartagena ColombiaGrupo Prometeus y Biomedicina Aplicada a las Ciencias Clínicas School of Medicine, Universidad de Cartagena Cartagena ColombiaInternational Coalition on Surgical Research Universidad Nacional Autónoma de Nicaragua Managua NicaraguaAbstract Introduction Colorectal cancer is the most common malignant neoplasm of the gastrointestinal tract. Its incidence and mortality vary markedly at a global level. Assessing the epidemiological behavior of this condition allows reevaluating diagnostic, therapeutic and prognostic options, based on new findings. In Colombia, few studies have correlated variables associated with surgical and oncological outcomes in this type of cancer. Then, the aim of this study was to evaluate the surgical outcomes and factors associated with postoperative complications of colorectal cancer in a Colombian Caribbean Population. Methods Retrospective cross‐sectional study, including patients with a histopathological diagnosis of colorectal cancer who underwent open or laparoscopic surgery, during a period of two years (2018–2020), from a regional referral hospital. Clinical history variables were collected. Frequencies and prevalence ratios were calculated. Results A total of 84 patients were finally included. Adenocarcinoma of non‐special type with advanced clinical stages was the most prevalent (72.6%). Rectal neoplasia (45.2%) was the most frequent anatomical subsite, followed by proximal colon (p = 0.026). The anatomical subsite of the neoplasm, intraoperative complication (PR 1.38; 95% CI, 1.21–1.59, p = 0.001) and intensive care stay (PR 1.062; 95% CI, 1.01–1.12, p = 0.048) were associated with postoperative outcome. Conclusions The anatomical subsite of the neoplasm location, the presence of intraoperative complications and the stay in intensive care may be associated with the surgical and oncological outcome of individuals with colon cancer from the Colombian Caribbean region.https://doi.org/10.1002/cnr2.1766colonic neoplasmsmortalitypostoperative complicationsrectal neoplasms |
| spellingShingle | Edgar Ernesto Vergara Dagobeth Gian Alberto Núñez Rojas Juan Carlos Hoyos Valdelamar Ivan David Lozada‐Martínez Amileth Suarez Causado Alexis Rafael Narvaez‐Rojas Surgical outcomes and factors associated with postoperative complications of colorectal cancer in a Colombian Caribbean population: Results from a regional referral hospital Cancer Reports colonic neoplasms mortality postoperative complications rectal neoplasms |
| title | Surgical outcomes and factors associated with postoperative complications of colorectal cancer in a Colombian Caribbean population: Results from a regional referral hospital |
| title_full | Surgical outcomes and factors associated with postoperative complications of colorectal cancer in a Colombian Caribbean population: Results from a regional referral hospital |
| title_fullStr | Surgical outcomes and factors associated with postoperative complications of colorectal cancer in a Colombian Caribbean population: Results from a regional referral hospital |
| title_full_unstemmed | Surgical outcomes and factors associated with postoperative complications of colorectal cancer in a Colombian Caribbean population: Results from a regional referral hospital |
| title_short | Surgical outcomes and factors associated with postoperative complications of colorectal cancer in a Colombian Caribbean population: Results from a regional referral hospital |
| title_sort | surgical outcomes and factors associated with postoperative complications of colorectal cancer in a colombian caribbean population results from a regional referral hospital |
| topic | colonic neoplasms mortality postoperative complications rectal neoplasms |
| url | https://doi.org/10.1002/cnr2.1766 |
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