Main properties of nanocrystalline hydroxyapatite as a bone graft material in treatment of periodontal defects. A review of literature

This study aims to provide a literature review on nanocrystalline hydroxyapatite (n-HA). n-HA constitutes the principle inorganic part of hard tissues. Therefore, preparation of commercial synthetic analogues, the so-called ‘biomimetic’, has gained a lot of attention since it can precisely mimic the...

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Main Authors: Mojtaba Bayani, Sepehr Torabi, Aysan Shahnaz, Mohammad Pourali
Format: Article
Language:English
Published: Taylor & Francis Group 2017-03-01
Series:Biotechnology & Biotechnological Equipment
Subjects:
Online Access:http://dx.doi.org/10.1080/13102818.2017.1281760
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author Mojtaba Bayani
Sepehr Torabi
Aysan Shahnaz
Mohammad Pourali
author_facet Mojtaba Bayani
Sepehr Torabi
Aysan Shahnaz
Mohammad Pourali
author_sort Mojtaba Bayani
collection DOAJ
description This study aims to provide a literature review on nanocrystalline hydroxyapatite (n-HA). n-HA constitutes the principle inorganic part of hard tissues. Therefore, preparation of commercial synthetic analogues, the so-called ‘biomimetic’, has gained a lot of attention since it can precisely mimic the physicochemical features of biological apatite compounds. Due to its improved osseointegrative properties, n-HA may represent a promising class of bone graft materials. n-HA binds to the bone and by stimulation of osteoblast activity and enhancing local growth factors it improves bone healing. Periodontitis is an inflammatory condition in response to microbial plaque that leads to periodontal tissue destruction and osseous defects in alveolar bone. A review of the extant literature reveals that n-HA has certain advantages in periodontal tissue regeneration including minimal patient morbidity, better biocompatibility, and lack of toxicity.
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spelling doaj.art-edc14b39f65d47f5baeebc020fd63cc62022-12-21T18:53:32ZengTaylor & Francis GroupBiotechnology & Biotechnological Equipment1310-28181314-35302017-03-0131221522010.1080/13102818.2017.12817601281760Main properties of nanocrystalline hydroxyapatite as a bone graft material in treatment of periodontal defects. A review of literatureMojtaba Bayani0Sepehr Torabi1Aysan Shahnaz2Mohammad Pourali3Arak University of Medical SciencesQazvin University of Medical SciencesQom University of Medical ScienceQom University of Medical SciencesThis study aims to provide a literature review on nanocrystalline hydroxyapatite (n-HA). n-HA constitutes the principle inorganic part of hard tissues. Therefore, preparation of commercial synthetic analogues, the so-called ‘biomimetic’, has gained a lot of attention since it can precisely mimic the physicochemical features of biological apatite compounds. Due to its improved osseointegrative properties, n-HA may represent a promising class of bone graft materials. n-HA binds to the bone and by stimulation of osteoblast activity and enhancing local growth factors it improves bone healing. Periodontitis is an inflammatory condition in response to microbial plaque that leads to periodontal tissue destruction and osseous defects in alveolar bone. A review of the extant literature reveals that n-HA has certain advantages in periodontal tissue regeneration including minimal patient morbidity, better biocompatibility, and lack of toxicity.http://dx.doi.org/10.1080/13102818.2017.1281760Nanocrystalline hydroxyapatitebone graftperiodontal defectsperiodontal regeneration
spellingShingle Mojtaba Bayani
Sepehr Torabi
Aysan Shahnaz
Mohammad Pourali
Main properties of nanocrystalline hydroxyapatite as a bone graft material in treatment of periodontal defects. A review of literature
Biotechnology & Biotechnological Equipment
Nanocrystalline hydroxyapatite
bone graft
periodontal defects
periodontal regeneration
title Main properties of nanocrystalline hydroxyapatite as a bone graft material in treatment of periodontal defects. A review of literature
title_full Main properties of nanocrystalline hydroxyapatite as a bone graft material in treatment of periodontal defects. A review of literature
title_fullStr Main properties of nanocrystalline hydroxyapatite as a bone graft material in treatment of periodontal defects. A review of literature
title_full_unstemmed Main properties of nanocrystalline hydroxyapatite as a bone graft material in treatment of periodontal defects. A review of literature
title_short Main properties of nanocrystalline hydroxyapatite as a bone graft material in treatment of periodontal defects. A review of literature
title_sort main properties of nanocrystalline hydroxyapatite as a bone graft material in treatment of periodontal defects a review of literature
topic Nanocrystalline hydroxyapatite
bone graft
periodontal defects
periodontal regeneration
url http://dx.doi.org/10.1080/13102818.2017.1281760
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