Ferulic acid suppresses interleukin‐1β‐induced degeneration of chondrocytes isolated from patients with osteoarthritis through the SIRT1/AMPK/PGC‐1α signaling pathway
Abstract Background Interleukin‐1β (IL‐1β) is involved in osteoarthritis pathogenesis and mediates a series of toxic processes including the production of matrix metalloproteinase and inflammatory regulators which are suppressed by activation of silent information regulator 1 (SIRT1). We aimed to de...
Main Authors: | Kewei Du, Xuchen Fang, Ziqiang Li |
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Format: | Article |
Language: | English |
Published: |
Wiley
2021-09-01
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Series: | Immunity, Inflammation and Disease |
Subjects: | |
Online Access: | https://doi.org/10.1002/iid3.424 |
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