Oligomer formation of SARS-CoV-2 ORF8 through 73YIDI76 motifs regulates immune response and non-infusion antiviral interactions
Introduction: Open Reading Frame 8 (ORF8) is a 121 amino acid length SARS-CoV-2 specific accessory protein that plays crucial roles in viral infectivity, and pathogenesis. Current SARS-CoV-2 treatments focus on spike or RNA-dependent RNA polymerase proteins. Hence, directing attention to ORF8 yields...
Main Authors: | Mohammad Assadizadeh, Maryam Azimzadeh Irani |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2023-11-01
|
Series: | Frontiers in Molecular Biosciences |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fmolb.2023.1270511/full |
Similar Items
-
Clinical characteristics and host immunity responses of SARS-CoV-2 Omicron variant BA.2 with deletion of ORF7a, ORF7b and ORF8
by: Zhizhong Tang, et al.
Published: (2023-05-01) -
SARS-CoV-2 ORF8 and SARS-CoV ORF8ab: Genomic Divergence and Functional Convergence
by: Sameer Mohammad, et al.
Published: (2020-08-01) -
Evaluation of the Variability of the ORF34, ORF68, and MLST Genes in EHV-1 from South Korea
by: Hyung-Woo Kang, et al.
Published: (2021-04-01) -
Phylogenetic Analysis of ORF Viruses From Five Contagious Ecthyma Outbreaks in Argentinian Goats
by: Andrea Peralta, et al.
Published: (2018-06-01) -
Discovery and Genomic Characterization of a 382-Nucleotide Deletion in ORF7b and ORF8 during the Early Evolution of SARS-CoV-2
by: Yvonne C. F. Su, et al.
Published: (2020-08-01)