Chemical Composition, Phytochemical Screening and Antioxidant Activity of <i>Acmella uliginosa</i> (Sw.) Cass Leaves
Acmella uliginosa (Sw.) Cass is widely used in traditional medicine and used in the treatment of many diseases. Extraction of component in leaves of Acmella uliginosa used methanol, ethyl acetate and n-hexane solvent. The percentage yield of extract from the leaves in methanol, ethyl acetate and n-h...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Department of Chemistry, Universitas Gadjah Mada
2016-08-01
|
| Series: | Indonesian Journal of Chemistry |
| Subjects: | |
| Online Access: | https://jurnal.ugm.ac.id/ijc/article/view/21160 |
| _version_ | 1818727525231099904 |
|---|---|
| author | Askal Maimulyanti Anton Restu Prihadi Iwan Safrudin |
| author_facet | Askal Maimulyanti Anton Restu Prihadi Iwan Safrudin |
| author_sort | Askal Maimulyanti |
| collection | DOAJ |
| description | Acmella uliginosa (Sw.) Cass is widely used in traditional medicine and used in the treatment of many diseases. Extraction of component in leaves of Acmella uliginosa used methanol, ethyl acetate and n-hexane solvent. The percentage yield of extract from the leaves in methanol, ethyl acetate and n-hexane were 6.50, 0.49, and 0.66, respectively. Analysis of component in various extracts of Acmella uliginosa (Sw.) Cass leaves used Gas Chromatography-Mass Spectrometry (GC-MS). The various classes of phytochemicals were identified from fractions of methanolic leaves extract by GC-MS. Qualitative analysis of phytochemical constituents in methanol, ethyl acetate and n-hexane extract were tannins, flavonoids, saponin, alkaloid and steroid. Antioxidant activity of Acmella uliginosa leaves from Indonesia was carried out by using 1,1,diphenyl-2-picryl-hydrazine (DPPH) free radical scavenging assay. The IC50 of three extract was calculated. A comparative study determined that Acmella uliginosa in ethyl acetate extract showed the highest antioxidant potential (IC50 = 28.09 µg/mL) compared to methanol extract (IC50 = 44.31 µg/mL) and n-hexane extract (181.23 µg/mL) against DPPH free radicals. |
| first_indexed | 2024-12-17T22:15:29Z |
| format | Article |
| id | doaj.art-edc881ab9f144b88b15be7a0909d86eb |
| institution | Directory Open Access Journal |
| issn | 1411-9420 2460-1578 |
| language | English |
| last_indexed | 2024-12-17T22:15:29Z |
| publishDate | 2016-08-01 |
| publisher | Department of Chemistry, Universitas Gadjah Mada |
| record_format | Article |
| series | Indonesian Journal of Chemistry |
| spelling | doaj.art-edc881ab9f144b88b15be7a0909d86eb2022-12-21T21:30:38ZengDepartment of Chemistry, Universitas Gadjah MadaIndonesian Journal of Chemistry1411-94202460-15782016-08-0116216217410.22146/ijc.2116014258Chemical Composition, Phytochemical Screening and Antioxidant Activity of <i>Acmella uliginosa</i> (Sw.) Cass LeavesAskal Maimulyanti0Anton Restu Prihadi1Iwan Safrudin2Department of Chemical Analysis, Academy of Analytical Chemistry (AKA), Jl. Pangeran Sogiri No. 283 Tanah Baru, Bogor 16158Department of Chemical Analysis, Academy of Analytical Chemistry (AKA), Jl. Pangeran Sogiri No. 283 Tanah Baru, Bogor 16158Department of R&D, PT Indesso Aroma, Jl. Alternatif Cibubur-Cileungsi Km. 9, Bogor 16820Acmella uliginosa (Sw.) Cass is widely used in traditional medicine and used in the treatment of many diseases. Extraction of component in leaves of Acmella uliginosa used methanol, ethyl acetate and n-hexane solvent. The percentage yield of extract from the leaves in methanol, ethyl acetate and n-hexane were 6.50, 0.49, and 0.66, respectively. Analysis of component in various extracts of Acmella uliginosa (Sw.) Cass leaves used Gas Chromatography-Mass Spectrometry (GC-MS). The various classes of phytochemicals were identified from fractions of methanolic leaves extract by GC-MS. Qualitative analysis of phytochemical constituents in methanol, ethyl acetate and n-hexane extract were tannins, flavonoids, saponin, alkaloid and steroid. Antioxidant activity of Acmella uliginosa leaves from Indonesia was carried out by using 1,1,diphenyl-2-picryl-hydrazine (DPPH) free radical scavenging assay. The IC50 of three extract was calculated. A comparative study determined that Acmella uliginosa in ethyl acetate extract showed the highest antioxidant potential (IC50 = 28.09 µg/mL) compared to methanol extract (IC50 = 44.31 µg/mL) and n-hexane extract (181.23 µg/mL) against DPPH free radicals.https://jurnal.ugm.ac.id/ijc/article/view/21160Acmella uliginosa (Sw.) Casschemical compositionphytochemicalantioxidant |
| spellingShingle | Askal Maimulyanti Anton Restu Prihadi Iwan Safrudin Chemical Composition, Phytochemical Screening and Antioxidant Activity of <i>Acmella uliginosa</i> (Sw.) Cass Leaves Indonesian Journal of Chemistry Acmella uliginosa (Sw.) Cass chemical composition phytochemical antioxidant |
| title | Chemical Composition, Phytochemical Screening and Antioxidant Activity of <i>Acmella uliginosa</i> (Sw.) Cass Leaves |
| title_full | Chemical Composition, Phytochemical Screening and Antioxidant Activity of <i>Acmella uliginosa</i> (Sw.) Cass Leaves |
| title_fullStr | Chemical Composition, Phytochemical Screening and Antioxidant Activity of <i>Acmella uliginosa</i> (Sw.) Cass Leaves |
| title_full_unstemmed | Chemical Composition, Phytochemical Screening and Antioxidant Activity of <i>Acmella uliginosa</i> (Sw.) Cass Leaves |
| title_short | Chemical Composition, Phytochemical Screening and Antioxidant Activity of <i>Acmella uliginosa</i> (Sw.) Cass Leaves |
| title_sort | chemical composition phytochemical screening and antioxidant activity of i acmella uliginosa i sw cass leaves |
| topic | Acmella uliginosa (Sw.) Cass chemical composition phytochemical antioxidant |
| url | https://jurnal.ugm.ac.id/ijc/article/view/21160 |
| work_keys_str_mv | AT askalmaimulyanti chemicalcompositionphytochemicalscreeningandantioxidantactivityofiacmellauliginosaiswcassleaves AT antonrestuprihadi chemicalcompositionphytochemicalscreeningandantioxidantactivityofiacmellauliginosaiswcassleaves AT iwansafrudin chemicalcompositionphytochemicalscreeningandantioxidantactivityofiacmellauliginosaiswcassleaves |