Automated SSHHPS Analysis Predicts a Potential Host Protein Target Common to Several Neuroinvasive (+)ssRNA Viruses

Automated SSHHPS Analysis Predicts a Potential Host Protein Target Common to Several Neuroinvasive (+)ssRNA Viruses

Within the viral genome, short stretches of homologous host pathogen sequences (SSHHPS) span the protease cleavage sites. To identify host proteins that may be cleaved during infection, we searched the human proteome for viral protease cleavage sites (~20 amino acids). We developed a <i>sequen...

Full description

Bibliographic Details
Main Authors: Katarina Z. Doctor, Elizabeth Gilmour, Marilyn Recarte, Trinity R. Beatty, Intisar Shifa, Michaela Stangel, Jacob Schwisow, Dagmar H. Leary, Patricia M. Legler
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Viruses
Subjects:
SSHHPS
SARS-CoV-2
neuroinvasive
virus
entry
protease
Online Access:https://www.mdpi.com/1999-4915/15/2/542

Internet

https://www.mdpi.com/1999-4915/15/2/542

Similar Items