Cepharanthine Ameliorates Pulmonary Fibrosis by Inhibiting the NF-κB/NLRP3 Pathway, Fibroblast-to-Myofibroblast Transition and Inflammation

Cepharanthine Ameliorates Pulmonary Fibrosis by Inhibiting the NF-κB/NLRP3 Pathway, Fibroblast-to-Myofibroblast Transition and Inflammation

Pulmonary fibrosis (PF) is one of the sequelae of Corona Virus Disease 2019 (COVID-19), and currently, lung transplantation is the only viable treatment option. Hence, other effective treatments are urgently required. We investigated the therapeutic effects of an approved botanical drug, cepharanthi...

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Bibliographic Details
Main Authors: Guangrui Chen, Jian Li, Huimeng Liu, Huiyu Zhou, Mingqiu Liu, Di Liang, Zhiyun Meng, Hui Gan, Zhuona Wu, Xiaoxia Zhu, Peng Han, Taoyun Liu, Ruolan Gu, Shuchen Liu, Guifang Dou
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Molecules
Subjects:
cepharanthine
pulmonary fibrosis
myofibroblast
NF-κB/NLRP3
COVID-19
Online Access:https://www.mdpi.com/1420-3049/28/2/753

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