Cocaine Gut: A Rare Case of Cocaine-Induced Esophageal, Gastric, and Small Bowel Necrosis
Cocaine is an indirect-acting sympathomimetic drug that inhibits norepinephrine and dopamine reuptake in the adrenergic presynaptic cleft. Cocaine use has been associated with strokes, angina, arrhythmias, and agitation. Data on gastrointestinal complications such as mesenteric ischemia, bowel necro...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2024-03-01
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| Series: | Journal of Investigative Medicine High Impact Case Reports |
| Online Access: | https://doi.org/10.1177/23247096241242569 |
| _version_ | 1827301718796271616 |
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| author | Lefika Bathobakae MD, MPH Sacide S. Ozgur MD Rammy Bashir MSc Tyler Wilkinson MSc Phenyo Phuu MD Ruhin Yuridullah MD Gabriel Melki MD Jessica Escobar MLS Sohail Qayyum MD |
| author_facet | Lefika Bathobakae MD, MPH Sacide S. Ozgur MD Rammy Bashir MSc Tyler Wilkinson MSc Phenyo Phuu MD Ruhin Yuridullah MD Gabriel Melki MD Jessica Escobar MLS Sohail Qayyum MD |
| author_sort | Lefika Bathobakae MD, MPH |
| collection | DOAJ |
| description | Cocaine is an indirect-acting sympathomimetic drug that inhibits norepinephrine and dopamine reuptake in the adrenergic presynaptic cleft. Cocaine use has been associated with strokes, angina, arrhythmias, and agitation. Data on gastrointestinal complications such as mesenteric ischemia, bowel necrosis, ulceration, and perforation are scarce. Here, we present a rare case of cocaine-induced esophageal, gastric, and small bowel necrosis that contributes to the limited literature on this subject. Diagnosis of cocaine-induced gastrointestinal complications involves a combination of imaging studies, laboratory assessments, and histopathological examinations. Timely surgical resection, supported by intravenous fluids, antibiotics, and pain management, is the mainstay of treatment. The prognosis varies but is significantly influenced by the promptness and effectiveness of the intervention, underscoring the importance of vigilant clinical care in such cases. |
| first_indexed | 2024-04-24T16:32:11Z |
| format | Article |
| id | doaj.art-edcfe3a9b75a4b23a4e3e5b61ac73641 |
| institution | Directory Open Access Journal |
| issn | 2324-7096 |
| language | English |
| last_indexed | 2024-04-24T16:32:11Z |
| publishDate | 2024-03-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Journal of Investigative Medicine High Impact Case Reports |
| spelling | doaj.art-edcfe3a9b75a4b23a4e3e5b61ac736412024-03-30T03:03:52ZengSAGE PublishingJournal of Investigative Medicine High Impact Case Reports2324-70962024-03-011210.1177/23247096241242569Cocaine Gut: A Rare Case of Cocaine-Induced Esophageal, Gastric, and Small Bowel NecrosisLefika Bathobakae MD, MPH0Sacide S. Ozgur MD1Rammy Bashir MSc2Tyler Wilkinson MSc3Phenyo Phuu MD4Ruhin Yuridullah MD5Gabriel Melki MD6Jessica Escobar MLS7Sohail Qayyum MD8St. Joseph’s University Medical Center, Paterson, NJ, USASt. Joseph’s University Medical Center, Paterson, NJ, USASt. George’s University School of Medicine, Grenada, West IndiesSt. George’s University School of Medicine, Grenada, West IndiesSt. George’s University School of Medicine, Grenada, West IndiesSt. Joseph’s University Medical Center, Paterson, NJ, USASt. Joseph’s University Medical Center, Paterson, NJ, USASt. Joseph’s University Medical Center, Paterson, NJ, USASt. Joseph’s University Medical Center, Paterson, NJ, USACocaine is an indirect-acting sympathomimetic drug that inhibits norepinephrine and dopamine reuptake in the adrenergic presynaptic cleft. Cocaine use has been associated with strokes, angina, arrhythmias, and agitation. Data on gastrointestinal complications such as mesenteric ischemia, bowel necrosis, ulceration, and perforation are scarce. Here, we present a rare case of cocaine-induced esophageal, gastric, and small bowel necrosis that contributes to the limited literature on this subject. Diagnosis of cocaine-induced gastrointestinal complications involves a combination of imaging studies, laboratory assessments, and histopathological examinations. Timely surgical resection, supported by intravenous fluids, antibiotics, and pain management, is the mainstay of treatment. The prognosis varies but is significantly influenced by the promptness and effectiveness of the intervention, underscoring the importance of vigilant clinical care in such cases.https://doi.org/10.1177/23247096241242569 |
| spellingShingle | Lefika Bathobakae MD, MPH Sacide S. Ozgur MD Rammy Bashir MSc Tyler Wilkinson MSc Phenyo Phuu MD Ruhin Yuridullah MD Gabriel Melki MD Jessica Escobar MLS Sohail Qayyum MD Cocaine Gut: A Rare Case of Cocaine-Induced Esophageal, Gastric, and Small Bowel Necrosis Journal of Investigative Medicine High Impact Case Reports |
| title | Cocaine Gut: A Rare Case of Cocaine-Induced Esophageal, Gastric, and Small Bowel Necrosis |
| title_full | Cocaine Gut: A Rare Case of Cocaine-Induced Esophageal, Gastric, and Small Bowel Necrosis |
| title_fullStr | Cocaine Gut: A Rare Case of Cocaine-Induced Esophageal, Gastric, and Small Bowel Necrosis |
| title_full_unstemmed | Cocaine Gut: A Rare Case of Cocaine-Induced Esophageal, Gastric, and Small Bowel Necrosis |
| title_short | Cocaine Gut: A Rare Case of Cocaine-Induced Esophageal, Gastric, and Small Bowel Necrosis |
| title_sort | cocaine gut a rare case of cocaine induced esophageal gastric and small bowel necrosis |
| url | https://doi.org/10.1177/23247096241242569 |
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