Phenotypic plasticity underlies local invasion and distant metastasis in colon cancer

Phenotypic plasticity underlies local invasion and distant metastasis in colon cancer

Phenotypic plasticity represents the most relevant hallmark of the carcinoma cell as it bestows it with the capacity of transiently altering its morphological and functional features while en route to the metastatic site. However, the study of phenotypic plasticity is hindered by the rarity of these...

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Bibliographic Details
Main Authors: Andrea Sacchetti, Miriam Teeuwssen, Mathijs Verhagen, Rosalie Joosten, Tong Xu, Roberto Stabile, Berdine van der Steen, Martin M Watson, Alem Gusinac, Won Kyu Kim, Inge Ubink, Harmen JG Van de Werken, Arianna Fumagalli, Madelon Paauwe, Jacco Van Rheenen, Owen J Sansom, Onno Kranenburg, Riccardo Fodde
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-05-01
Series:eLife
Subjects:
partial EMT
colon cancer
phenotypic plasticity
Online Access:https://elifesciences.org/articles/61461

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