Structural and Functional Features of the P2X4 Receptor: An Immunological Perspective
Extracellular nucleotides are important mediators of activation, triggering various responses through plasma membrane P2 and P1 receptors. P2 receptors are further subdivided into ionotropic P2X receptors and G protein-coupled P2Y receptors. P2X4 is an ATP-gated cation channel broadly expressed in m...
Main Authors: | Jean M. Kanellopoulos, Cássio Luiz Coutinho Almeida-da-Silva, Sirje Rüütel Boudinot, David M. Ojcius |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2021-03-01
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Series: | Frontiers in Immunology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fimmu.2021.645834/full |
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