Nasal Obstruction Symptom Evaluation Score Analysis: Exploring Nasal Function in Premenopausal versus Postmenopausal Indian Women

Background: Menopause brings about significant hormonal changes that can affect various aspects of women’s health, including nasal function. However, the specific impact of menopause on nasal health in Indian women remains underexplored. This study aims to compare nasal function using the Nasal Obst...

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Үндсэн зохиолчид: Akhil Pratap Singh, Amit Varshney, Ruchika Garg, Prabhat Agrawal
Формат: Өгүүллэг
Хэл сонгох:English
Хэвлэсэн: Wolters Kluwer Medknow Publications 2024-10-01
Цуврал:Journal of Mid-Life Health
Нөхцлүүд:
Онлайн хандалт:https://journals.lww.com/10.4103/jmh.jmh_126_24
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author Akhil Pratap Singh
Amit Varshney
Ruchika Garg
Prabhat Agrawal
author_facet Akhil Pratap Singh
Amit Varshney
Ruchika Garg
Prabhat Agrawal
author_sort Akhil Pratap Singh
collection DOAJ
description Background: Menopause brings about significant hormonal changes that can affect various aspects of women’s health, including nasal function. However, the specific impact of menopause on nasal health in Indian women remains underexplored. This study aims to compare nasal function using the Nasal Obstruction Symptom Evaluation (NOSE) score between premenopausal and postmenopausal Indian women. Materials and Methods: A comparative cross-sectional study was conducted involving 107 premenopausal and 111 postmenopausal women recruited from a tertiary care hospital in India. Demographic data, medical history, and NOSE scores were collected. Statistical analyses including Wilcoxon rank-sum test, Chi-squared test, logistic regression, and receiver operating characteristic curve analysis were performed. Results: Postmenopausal women were significantly older with higher body mass index (BMI) compared to premenopausal women. Postmenopausal women consistently had higher NOSE scores indicating worse nasal function across various time points. Logistic regression revealed menopausal status as a significant predictor of severe nasal obstruction (odds ratio: 1.45, 95% confidence interval: 1.10–1.90, P = 0.015), independent of age, BMI, and other factors. Conclusion: Menopause is associated with a significant decline in nasal function in Indian women, as evidenced by higher NOSE scores in postmenopausal women. Addressing nasal symptoms in postmenopausal women may improve their quality of life. Further research is needed to develop targeted interventions for managing nasal obstruction in this population.
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spelling doaj.art-edd8343db76a4e76b51a2fe7d14268fe2025-03-04T13:45:18ZengWolters Kluwer Medknow PublicationsJournal of Mid-Life Health0976-78000976-78192024-10-0115424524910.4103/jmh.jmh_126_24Nasal Obstruction Symptom Evaluation Score Analysis: Exploring Nasal Function in Premenopausal versus Postmenopausal Indian WomenAkhil Pratap SinghAmit VarshneyRuchika GargPrabhat AgrawalBackground: Menopause brings about significant hormonal changes that can affect various aspects of women’s health, including nasal function. However, the specific impact of menopause on nasal health in Indian women remains underexplored. This study aims to compare nasal function using the Nasal Obstruction Symptom Evaluation (NOSE) score between premenopausal and postmenopausal Indian women. Materials and Methods: A comparative cross-sectional study was conducted involving 107 premenopausal and 111 postmenopausal women recruited from a tertiary care hospital in India. Demographic data, medical history, and NOSE scores were collected. Statistical analyses including Wilcoxon rank-sum test, Chi-squared test, logistic regression, and receiver operating characteristic curve analysis were performed. Results: Postmenopausal women were significantly older with higher body mass index (BMI) compared to premenopausal women. Postmenopausal women consistently had higher NOSE scores indicating worse nasal function across various time points. Logistic regression revealed menopausal status as a significant predictor of severe nasal obstruction (odds ratio: 1.45, 95% confidence interval: 1.10–1.90, P = 0.015), independent of age, BMI, and other factors. Conclusion: Menopause is associated with a significant decline in nasal function in Indian women, as evidenced by higher NOSE scores in postmenopausal women. Addressing nasal symptoms in postmenopausal women may improve their quality of life. Further research is needed to develop targeted interventions for managing nasal obstruction in this population.https://journals.lww.com/10.4103/jmh.jmh_126_24menopausenasal functionnasal obstruction symptom evaluation score
spellingShingle Akhil Pratap Singh
Amit Varshney
Ruchika Garg
Prabhat Agrawal
Nasal Obstruction Symptom Evaluation Score Analysis: Exploring Nasal Function in Premenopausal versus Postmenopausal Indian Women
Journal of Mid-Life Health
menopause
nasal function
nasal obstruction symptom evaluation score
title Nasal Obstruction Symptom Evaluation Score Analysis: Exploring Nasal Function in Premenopausal versus Postmenopausal Indian Women
title_full Nasal Obstruction Symptom Evaluation Score Analysis: Exploring Nasal Function in Premenopausal versus Postmenopausal Indian Women
title_fullStr Nasal Obstruction Symptom Evaluation Score Analysis: Exploring Nasal Function in Premenopausal versus Postmenopausal Indian Women
title_full_unstemmed Nasal Obstruction Symptom Evaluation Score Analysis: Exploring Nasal Function in Premenopausal versus Postmenopausal Indian Women
title_short Nasal Obstruction Symptom Evaluation Score Analysis: Exploring Nasal Function in Premenopausal versus Postmenopausal Indian Women
title_sort nasal obstruction symptom evaluation score analysis exploring nasal function in premenopausal versus postmenopausal indian women
topic menopause
nasal function
nasal obstruction symptom evaluation score
url https://journals.lww.com/10.4103/jmh.jmh_126_24
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AT amitvarshney nasalobstructionsymptomevaluationscoreanalysisexploringnasalfunctioninpremenopausalversuspostmenopausalindianwomen
AT ruchikagarg nasalobstructionsymptomevaluationscoreanalysisexploringnasalfunctioninpremenopausalversuspostmenopausalindianwomen
AT prabhatagrawal nasalobstructionsymptomevaluationscoreanalysisexploringnasalfunctioninpremenopausalversuspostmenopausalindianwomen