GASOTRANSMITTERS: FROM THE TOXIC EFFECTS TO THE REGULATION OF CELLULAR FUNCTION AND CLINICAL APPLICATION
Nitric oxide II (NO), carbon monoxide (СО) and hydrogen sulfide (H2S) for many decades were described as the toxic gases inducing damaging action in man’s organisms. Recently it was found that NO, CO and H2S endogenously synthesized and served as signaling molecules of autocrine and paracrine regula...
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Format: | Article |
Language: | English |
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Siberian State Medical University (Tomsk)
2014-12-01
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Series: | Бюллетень сибирской медицины |
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Online Access: | https://bulletin.ssmu.ru/jour/article/view/178 |
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author | G. F. Sitdikova A. V. Yakovlev A. L. Zefirov |
author_facet | G. F. Sitdikova A. V. Yakovlev A. L. Zefirov |
author_sort | G. F. Sitdikova |
collection | DOAJ |
description | Nitric oxide II (NO), carbon monoxide (СО) and hydrogen sulfide (H2S) for many decades were described as the toxic gases inducing damaging action in man’s organisms. Recently it was found that NO, CO and H2S endogenously synthesized and served as signaling molecules of autocrine and paracrine regulation in many systems. The properties, mechanisms of synthesis and action in excitable systems are presented in this paper. Besides we also descried our results concerning the effects and mechanisms of action of gaseous messengers in peripheral nervous system – in neuromuscular junction. |
first_indexed | 2024-04-10T01:08:09Z |
format | Article |
id | doaj.art-eddaea1762c44a4786692df6ae6d1d76 |
institution | Directory Open Access Journal |
issn | 1682-0363 1819-3684 |
language | English |
last_indexed | 2024-04-10T01:08:09Z |
publishDate | 2014-12-01 |
publisher | Siberian State Medical University (Tomsk) |
record_format | Article |
series | Бюллетень сибирской медицины |
spelling | doaj.art-eddaea1762c44a4786692df6ae6d1d762023-03-13T09:58:20ZengSiberian State Medical University (Tomsk)Бюллетень сибирской медицины1682-03631819-36842014-12-0113618520010.20538/1682-0363-2014-6-185-200176GASOTRANSMITTERS: FROM THE TOXIC EFFECTS TO THE REGULATION OF CELLULAR FUNCTION AND CLINICAL APPLICATIONG. F. Sitdikova0A. V. Yakovlev1A. L. Zefirov2Казанский (Приволжский) федеральный университет, Институт фундаментальной медицины и биологии; Казань Казанский государственный медицинский университет, КазаньКазанский (Приволжский) федеральный университет, Институт фундаментальной медицины и биологии; Казань Казанский государственный медицинский университет, КазаньКазанский (Приволжский) федеральный университет, Институт фундаментальной медицины и биологии; Казань Казанский государственный медицинский университет, КазаньNitric oxide II (NO), carbon monoxide (СО) and hydrogen sulfide (H2S) for many decades were described as the toxic gases inducing damaging action in man’s organisms. Recently it was found that NO, CO and H2S endogenously synthesized and served as signaling molecules of autocrine and paracrine regulation in many systems. The properties, mechanisms of synthesis and action in excitable systems are presented in this paper. Besides we also descried our results concerning the effects and mechanisms of action of gaseous messengers in peripheral nervous system – in neuromuscular junction.https://bulletin.ssmu.ru/jour/article/view/178рнф |
spellingShingle | G. F. Sitdikova A. V. Yakovlev A. L. Zefirov GASOTRANSMITTERS: FROM THE TOXIC EFFECTS TO THE REGULATION OF CELLULAR FUNCTION AND CLINICAL APPLICATION Бюллетень сибирской медицины рнф |
title | GASOTRANSMITTERS: FROM THE TOXIC EFFECTS TO THE REGULATION OF CELLULAR FUNCTION AND CLINICAL APPLICATION |
title_full | GASOTRANSMITTERS: FROM THE TOXIC EFFECTS TO THE REGULATION OF CELLULAR FUNCTION AND CLINICAL APPLICATION |
title_fullStr | GASOTRANSMITTERS: FROM THE TOXIC EFFECTS TO THE REGULATION OF CELLULAR FUNCTION AND CLINICAL APPLICATION |
title_full_unstemmed | GASOTRANSMITTERS: FROM THE TOXIC EFFECTS TO THE REGULATION OF CELLULAR FUNCTION AND CLINICAL APPLICATION |
title_short | GASOTRANSMITTERS: FROM THE TOXIC EFFECTS TO THE REGULATION OF CELLULAR FUNCTION AND CLINICAL APPLICATION |
title_sort | gasotransmitters from the toxic effects to the regulation of cellular function and clinical application |
topic | рнф |
url | https://bulletin.ssmu.ru/jour/article/view/178 |
work_keys_str_mv | AT gfsitdikova gasotransmittersfromthetoxiceffectstotheregulationofcellularfunctionandclinicalapplication AT avyakovlev gasotransmittersfromthetoxiceffectstotheregulationofcellularfunctionandclinicalapplication AT alzefirov gasotransmittersfromthetoxiceffectstotheregulationofcellularfunctionandclinicalapplication |