Modulating the tumor microenvironment improves antitumor effect of anti-PD-L1 mAb in breast cancer

Modulating the tumor microenvironment improves antitumor effect of anti-PD-L1 mAb in breast cancer

Introduction: Immune checkpoint inhibitors (ICIs) have provided noteworthy benefits in multiple cancer patients. However, the efficacy of monotherapy of ICIs was very limited. In this study, we endeavored to explore whether losartan can modulate the solid tumor microenvironment (TME) and improve the...

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Bibliographic Details
Main Authors: Xiuying Li, Xianqin Luo, Shunqin Hu
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2023-03-01
Series:BioImpacts
Subjects:
anti-pd-l1 mab
losartan
tumor microenvironment
immunotherapy
Online Access:https://bi.tbzmed.ac.ir/PDF/bi-13-89.pdf

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