POSSIBILITIES OF USE OF THE MODERN ANTIHISTAMINE MEDICINES IN THERAPY OF PATIENTS WITH ALLERGIC RHINITIS

Allergic rhinitis as one of the most common non-infectious respiratory inflammatory diseases is a global public health problem. The course of allergic rhinitis, its effect on the pathology of other organs and systems, the likelihood of complications and many other aspects of this pathology are large...

Full description

Bibliographic Details
Main Authors: G. N. Nikiforova, V. M. Svistushkin, A. N. Slavsky, D. M. Pshonkina
Format: Article
Language:Russian
Published: Remedium Group LLC 2017-05-01
Series:Медицинский совет
Subjects:
Online Access:https://www.med-sovet.pro/jour/article/view/1833
_version_ 1797841399768416256
author G. N. Nikiforova
V. M. Svistushkin
A. N. Slavsky
D. M. Pshonkina
author_facet G. N. Nikiforova
V. M. Svistushkin
A. N. Slavsky
D. M. Pshonkina
author_sort G. N. Nikiforova
collection DOAJ
description Allergic rhinitis as one of the most common non-infectious respiratory inflammatory diseases is a global public health problem. The course of allergic rhinitis, its effect on the pathology of other organs and systems, the likelihood of complications and many other aspects of this pathology are largely determined by timely diagnosis and adequate treatment. At the heart of the pathogenesis of allergic rhinitis is the immediate allergic reaction. Histamine is the most important biogenic amine, the physiological regulator of the activity of various cells and systems and one of the main mediators of allergic reactions of immediate type. In the treatment of allergic rhinitis, one of the key places is occupied by antihistamines. One of such highly effective modern antihistamines is levocetirizine – a blocker of H1 histamine receptors of the second generation. Leveltzetirizine affects the histamine-dependent stage of allergic reactions, reduces vascular permeability and eosinophil migration, limits the release of inflammatory mediators, significantly influences the formation of edema of the tissues and the production of mucus, prevents development and greatly facilitates the course of the allergic reaction, has antiexudative, antipruritic and anti-inflammatory effects, and a pronounced ability to eliminate nasal obstruction in patients with seasonal allergic rhinitis. The drug levocetirizine Allerway®, bioequivalent to the original drug, is of definite interest to physicians of various specialties.
first_indexed 2024-04-09T16:30:13Z
format Article
id doaj.art-eddd8e9c803a4defbb46c9ad0cdd6af6
institution Directory Open Access Journal
issn 2079-701X
2658-5790
language Russian
last_indexed 2024-04-09T16:30:13Z
publishDate 2017-05-01
publisher Remedium Group LLC
record_format Article
series Медицинский совет
spelling doaj.art-eddd8e9c803a4defbb46c9ad0cdd6af62023-04-23T06:57:09ZrusRemedium Group LLCМедицинский совет2079-701X2658-57902017-05-0108929810.21518/2079-701X-2017-8-92-981811POSSIBILITIES OF USE OF THE MODERN ANTIHISTAMINE MEDICINES IN THERAPY OF PATIENTS WITH ALLERGIC RHINITISG. N. Nikiforova0V. M. Svistushkin1A. N. Slavsky2D. M. Pshonkina3First Moscow state medical university to them I. M. SechenovFirst Moscow state medical university to them I. M. SechenovFirst Moscow state medical university to them I. M. SechenovFirst Moscow state medical university to them I. M. SechenovAllergic rhinitis as one of the most common non-infectious respiratory inflammatory diseases is a global public health problem. The course of allergic rhinitis, its effect on the pathology of other organs and systems, the likelihood of complications and many other aspects of this pathology are largely determined by timely diagnosis and adequate treatment. At the heart of the pathogenesis of allergic rhinitis is the immediate allergic reaction. Histamine is the most important biogenic amine, the physiological regulator of the activity of various cells and systems and one of the main mediators of allergic reactions of immediate type. In the treatment of allergic rhinitis, one of the key places is occupied by antihistamines. One of such highly effective modern antihistamines is levocetirizine – a blocker of H1 histamine receptors of the second generation. Leveltzetirizine affects the histamine-dependent stage of allergic reactions, reduces vascular permeability and eosinophil migration, limits the release of inflammatory mediators, significantly influences the formation of edema of the tissues and the production of mucus, prevents development and greatly facilitates the course of the allergic reaction, has antiexudative, antipruritic and anti-inflammatory effects, and a pronounced ability to eliminate nasal obstruction in patients with seasonal allergic rhinitis. The drug levocetirizine Allerway®, bioequivalent to the original drug, is of definite interest to physicians of various specialties.https://www.med-sovet.pro/jour/article/view/1833allergic rhinitisnasal obstructionquality of lifehistaminepathogenetic treatmentantihistamineslevocetirizineallerway®
spellingShingle G. N. Nikiforova
V. M. Svistushkin
A. N. Slavsky
D. M. Pshonkina
POSSIBILITIES OF USE OF THE MODERN ANTIHISTAMINE MEDICINES IN THERAPY OF PATIENTS WITH ALLERGIC RHINITIS
Медицинский совет
allergic rhinitis
nasal obstruction
quality of life
histamine
pathogenetic treatment
antihistamines
levocetirizine
allerway®
title POSSIBILITIES OF USE OF THE MODERN ANTIHISTAMINE MEDICINES IN THERAPY OF PATIENTS WITH ALLERGIC RHINITIS
title_full POSSIBILITIES OF USE OF THE MODERN ANTIHISTAMINE MEDICINES IN THERAPY OF PATIENTS WITH ALLERGIC RHINITIS
title_fullStr POSSIBILITIES OF USE OF THE MODERN ANTIHISTAMINE MEDICINES IN THERAPY OF PATIENTS WITH ALLERGIC RHINITIS
title_full_unstemmed POSSIBILITIES OF USE OF THE MODERN ANTIHISTAMINE MEDICINES IN THERAPY OF PATIENTS WITH ALLERGIC RHINITIS
title_short POSSIBILITIES OF USE OF THE MODERN ANTIHISTAMINE MEDICINES IN THERAPY OF PATIENTS WITH ALLERGIC RHINITIS
title_sort possibilities of use of the modern antihistamine medicines in therapy of patients with allergic rhinitis
topic allergic rhinitis
nasal obstruction
quality of life
histamine
pathogenetic treatment
antihistamines
levocetirizine
allerway®
url https://www.med-sovet.pro/jour/article/view/1833
work_keys_str_mv AT gnnikiforova possibilitiesofuseofthemodernantihistaminemedicinesintherapyofpatientswithallergicrhinitis
AT vmsvistushkin possibilitiesofuseofthemodernantihistaminemedicinesintherapyofpatientswithallergicrhinitis
AT anslavsky possibilitiesofuseofthemodernantihistaminemedicinesintherapyofpatientswithallergicrhinitis
AT dmpshonkina possibilitiesofuseofthemodernantihistaminemedicinesintherapyofpatientswithallergicrhinitis