OCD in animal models using quinpirole as dopaminergic inductor of perseverative behaviour
In the reviewed articles, quinpirole is used as a dopamine D2 and D3 receptor agonist to induce persistent behaviour in animal models. Dopamine has been related to perseverative behaviour. The perseverative behaviour was observed in an open field with objects of different shapes and sizes. The main...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Permanyer
2015-10-01
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| Series: | Revista Médica del Hospital General de México |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0185106315000736 |
| _version_ | 1811335857346445312 |
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| author | C. Campos-García Rojas F. Jiménez-Ponce A. Flores-Vargas A.P. García |
| author_facet | C. Campos-García Rojas F. Jiménez-Ponce A. Flores-Vargas A.P. García |
| author_sort | C. Campos-García Rojas |
| collection | DOAJ |
| description | In the reviewed articles, quinpirole is used as a dopamine D2 and D3 receptor agonist to induce persistent behaviour in animal models. Dopamine has been related to perseverative behaviour. The perseverative behaviour was observed in an open field with objects of different shapes and sizes. The main structures studied with this methodology are the orbitofrontal cortex, striatum, thalamus, basolateral amygdala and nucleus accumbens. The animal models studied comply with the face, predictive and construct validity. |
| first_indexed | 2024-04-13T17:30:06Z |
| format | Article |
| id | doaj.art-ede2b65c7f9c46fb86c7a642e56f4cff |
| institution | Directory Open Access Journal |
| issn | 0185-1063 |
| language | English |
| last_indexed | 2024-04-13T17:30:06Z |
| publishDate | 2015-10-01 |
| publisher | Permanyer |
| record_format | Article |
| series | Revista Médica del Hospital General de México |
| spelling | doaj.art-ede2b65c7f9c46fb86c7a642e56f4cff2022-12-22T02:37:36ZengPermanyerRevista Médica del Hospital General de México0185-10632015-10-0178416917610.1016/j.hgmx.2015.09.002OCD in animal models using quinpirole as dopaminergic inductor of perseverative behaviourC. Campos-García Rojas0F. Jiménez-Ponce1A. Flores-Vargas2A.P. García3Servicio de Cirugía Experimental del Hospital General de México “Dr. Eduardo Liceaga”, Neurocirugía Clínica, Hospital Ángeles del Pedregal, Servicio Social en Investigación de la Universidad Autónoma del Estado de México, Servicio de Cirugía Experimental del Hospital General de México “Dr. Eduardo Liceaga”, In the reviewed articles, quinpirole is used as a dopamine D2 and D3 receptor agonist to induce persistent behaviour in animal models. Dopamine has been related to perseverative behaviour. The perseverative behaviour was observed in an open field with objects of different shapes and sizes. The main structures studied with this methodology are the orbitofrontal cortex, striatum, thalamus, basolateral amygdala and nucleus accumbens. The animal models studied comply with the face, predictive and construct validity.http://www.sciencedirect.com/science/article/pii/S0185106315000736QuinpiroleObsessive compulsive disorderRatOpen field |
| spellingShingle | C. Campos-García Rojas F. Jiménez-Ponce A. Flores-Vargas A.P. García OCD in animal models using quinpirole as dopaminergic inductor of perseverative behaviour Revista Médica del Hospital General de México Quinpirole Obsessive compulsive disorder Rat Open field |
| title | OCD in animal models using quinpirole as dopaminergic inductor of perseverative behaviour |
| title_full | OCD in animal models using quinpirole as dopaminergic inductor of perseverative behaviour |
| title_fullStr | OCD in animal models using quinpirole as dopaminergic inductor of perseverative behaviour |
| title_full_unstemmed | OCD in animal models using quinpirole as dopaminergic inductor of perseverative behaviour |
| title_short | OCD in animal models using quinpirole as dopaminergic inductor of perseverative behaviour |
| title_sort | ocd in animal models using quinpirole as dopaminergic inductor of perseverative behaviour |
| topic | Quinpirole Obsessive compulsive disorder Rat Open field |
| url | http://www.sciencedirect.com/science/article/pii/S0185106315000736 |
| work_keys_str_mv | AT ccamposgarciarojas ocdinanimalmodelsusingquinpiroleasdopaminergicinductorofperseverativebehaviour AT fjimenezponce ocdinanimalmodelsusingquinpiroleasdopaminergicinductorofperseverativebehaviour AT afloresvargas ocdinanimalmodelsusingquinpiroleasdopaminergicinductorofperseverativebehaviour AT apgarcia ocdinanimalmodelsusingquinpiroleasdopaminergicinductorofperseverativebehaviour |