The Efficacy of V. odorata Extract in the Treatment of Insomnia: A Systematic Review and Meta-Analysis
AimThis systematic review and meta-analysis was performed to assess the effect of Viola odorata (V. odorata) extract in the treatment of insomnia.MethodsPubMed, EMBASE, and Cochrane Library databases, as well as references of related articles, were searched. Finally, four articles with five clinical...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-06-01
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| Series: | Frontiers in Neurology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fneur.2022.730311/full |
| _version_ | 1818470065130962944 |
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| author | Shuangfeng Huang Qianqian Huang Zhongbao Zhou Junliang Zhang Yan Zhan Zhigang Liang |
| author_facet | Shuangfeng Huang Qianqian Huang Zhongbao Zhou Junliang Zhang Yan Zhan Zhigang Liang |
| author_sort | Shuangfeng Huang |
| collection | DOAJ |
| description | AimThis systematic review and meta-analysis was performed to assess the effect of Viola odorata (V. odorata) extract in the treatment of insomnia.MethodsPubMed, EMBASE, and Cochrane Library databases, as well as references of related articles, were searched. Finally, four articles with five clinical trials including 224 patients were included in the analysis.ResultsThe obtained results indicated a greater improvement in total PSQI scores (MD,−4.67; P = 0.0002), subjective sleep quality score (MD,−0.91; P = 0.003), sleep duration score (MD,−0.77; P < 0.00001), and ISI score (MD,−6.30; P = 0.009) in the Viola extract group compared with the placebo group. However, the Viola extract group did not significantly differ in sleep latency (MD,−0.85; P = 0.08), habitual sleep efficiency (MD,−0.61; P = 0.21), sleep disturbances (MD,−0.36; P = 0.11), and daytime dysfunction (MD,−0.94; P = 0.12) from the placebo group.ConclusionsViola extract supplement led to a greater improvement in total PSQI scores, subjective sleep quality score, sleep duration score, and ISI score compared with the placebo group of patients with chronic insomnia. |
| first_indexed | 2024-04-13T21:32:55Z |
| format | Article |
| id | doaj.art-ede5ffdcdcd6415fb5ed0d91444f0603 |
| institution | Directory Open Access Journal |
| issn | 1664-2295 |
| language | English |
| last_indexed | 2024-04-13T21:32:55Z |
| publishDate | 2022-06-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neurology |
| spelling | doaj.art-ede5ffdcdcd6415fb5ed0d91444f06032022-12-22T02:29:05ZengFrontiers Media S.A.Frontiers in Neurology1664-22952022-06-011310.3389/fneur.2022.730311730311The Efficacy of V. odorata Extract in the Treatment of Insomnia: A Systematic Review and Meta-AnalysisShuangfeng Huang0Qianqian Huang1Zhongbao Zhou2Junliang Zhang3Yan Zhan4Zhigang Liang5The Second Clinical Medical College, Binzhou Medical University, Yantai, ChinaDepartment of Gastroenterology, People's Hospital of Jimo District, Qingdao, ChinaBeijing TianTan Hospital, Capital Medical University, Beijing, ChinaDepartment of Neurology, The Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai, ChinaDepartment of Neurology, Yantai Affiliated Hospital of Binzhou Medical University, The Second Clinical Medical College of Binzhou Medical University, Yantai, ChinaDepartment of Neurology, The Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai, ChinaAimThis systematic review and meta-analysis was performed to assess the effect of Viola odorata (V. odorata) extract in the treatment of insomnia.MethodsPubMed, EMBASE, and Cochrane Library databases, as well as references of related articles, were searched. Finally, four articles with five clinical trials including 224 patients were included in the analysis.ResultsThe obtained results indicated a greater improvement in total PSQI scores (MD,−4.67; P = 0.0002), subjective sleep quality score (MD,−0.91; P = 0.003), sleep duration score (MD,−0.77; P < 0.00001), and ISI score (MD,−6.30; P = 0.009) in the Viola extract group compared with the placebo group. However, the Viola extract group did not significantly differ in sleep latency (MD,−0.85; P = 0.08), habitual sleep efficiency (MD,−0.61; P = 0.21), sleep disturbances (MD,−0.36; P = 0.11), and daytime dysfunction (MD,−0.94; P = 0.12) from the placebo group.ConclusionsViola extract supplement led to a greater improvement in total PSQI scores, subjective sleep quality score, sleep duration score, and ISI score compared with the placebo group of patients with chronic insomnia.https://www.frontiersin.org/articles/10.3389/fneur.2022.730311/fullsystematic review and meta-analysisViola extractinsomniaPittsburgh Sleep Quality Indexinsomnia severity index |
| spellingShingle | Shuangfeng Huang Qianqian Huang Zhongbao Zhou Junliang Zhang Yan Zhan Zhigang Liang The Efficacy of V. odorata Extract in the Treatment of Insomnia: A Systematic Review and Meta-Analysis Frontiers in Neurology systematic review and meta-analysis Viola extract insomnia Pittsburgh Sleep Quality Index insomnia severity index |
| title | The Efficacy of V. odorata Extract in the Treatment of Insomnia: A Systematic Review and Meta-Analysis |
| title_full | The Efficacy of V. odorata Extract in the Treatment of Insomnia: A Systematic Review and Meta-Analysis |
| title_fullStr | The Efficacy of V. odorata Extract in the Treatment of Insomnia: A Systematic Review and Meta-Analysis |
| title_full_unstemmed | The Efficacy of V. odorata Extract in the Treatment of Insomnia: A Systematic Review and Meta-Analysis |
| title_short | The Efficacy of V. odorata Extract in the Treatment of Insomnia: A Systematic Review and Meta-Analysis |
| title_sort | efficacy of v odorata extract in the treatment of insomnia a systematic review and meta analysis |
| topic | systematic review and meta-analysis Viola extract insomnia Pittsburgh Sleep Quality Index insomnia severity index |
| url | https://www.frontiersin.org/articles/10.3389/fneur.2022.730311/full |
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