Proteome dynamics during homeostatic scaling in cultured neurons

Proteome dynamics during homeostatic scaling in cultured neurons

Protein turnover, the net result of protein synthesis and degradation, enables cells to remodel their proteomes in response to internal and external cues. Previously, we analyzed protein turnover rates in cultured brain cells under basal neuronal activity and found that protein turnover is influence...

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Bibliographic Details
Main Authors: Aline Ricarda Dörrbaum, Beatriz Alvarez-Castelao, Belquis Nassim-Assir, Julian D Langer, Erin M Schuman
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-04-01
Series:eLife
Subjects:
protein synthesis
protein degradation
synaptic scaling
protein turnover
homeostasis
Online Access:https://elifesciences.org/articles/52939

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