Longitudinal assessment of D-dimer and plasminogen activator inhibitor type-1 plasma levels in pregnant women with risk factors for preeclampsia
Objective: Investigating D-Dimer/D-Di and plasminogen activator inhibitor type-1/PAI-1 levels throughout gestation in women with preeclampsia/PE risk factors. Methods: D-Di and PAI-1 plasma levels were determined in 28 women at 12–19, 20–29, 30–34 and 35–40 weeks of gestation. Results: D-Di was lowe...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2019-01-01
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| Series: | Hypertension in Pregnancy |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/10641955.2019.1577435 |
| _version_ | 1797681618701254656 |
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| author | Flávia Campos Lucena Eura Martins Lage Patrícia Gonçalves Teixeira Alexandre Simões Barbosa Rejane Diniz Bashir Lwaleed André Talvani Patrícia Nessralla Alpoim Luiza Oliveira Perucci Luci Maria SantAna Dusse |
| author_facet | Flávia Campos Lucena Eura Martins Lage Patrícia Gonçalves Teixeira Alexandre Simões Barbosa Rejane Diniz Bashir Lwaleed André Talvani Patrícia Nessralla Alpoim Luiza Oliveira Perucci Luci Maria SantAna Dusse |
| author_sort | Flávia Campos Lucena |
| collection | DOAJ |
| description | Objective: Investigating D-Dimer/D-Di and plasminogen activator inhibitor type-1/PAI-1 levels throughout gestation in women with preeclampsia/PE risk factors. Methods: D-Di and PAI-1 plasma levels were determined in 28 women at 12–19, 20–29, 30–34 and 35–40 weeks of gestation. Results: D-Di was lower at 12–19 weeks and higher at 30–34 weeks in women who developed PE versus who did not develop it. D-Di increased throughout gestation in both groups, peaking earlier in pregnant women who developed PE versus who did not develop it. PA1-1 increased across gestation, but it didn’t differ between groups. Conclusion: D-Di was able to discriminate these groups of women at 12–19 and 30–34 weeks of gestation. |
| first_indexed | 2024-03-11T23:47:29Z |
| format | Article |
| id | doaj.art-edeb4af8a0014c8fa9e320898f0dd122 |
| institution | Directory Open Access Journal |
| issn | 1064-1955 1525-6065 |
| language | English |
| last_indexed | 2024-03-11T23:47:29Z |
| publishDate | 2019-01-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Hypertension in Pregnancy |
| spelling | doaj.art-edeb4af8a0014c8fa9e320898f0dd1222023-09-19T09:24:42ZengTaylor & Francis GroupHypertension in Pregnancy1064-19551525-60652019-01-01381586310.1080/10641955.2019.15774351577435Longitudinal assessment of D-dimer and plasminogen activator inhibitor type-1 plasma levels in pregnant women with risk factors for preeclampsiaFlávia Campos Lucena0Eura Martins Lage1Patrícia Gonçalves Teixeira2Alexandre Simões Barbosa3Rejane Diniz4Bashir Lwaleed5André Talvani6Patrícia Nessralla Alpoim7Luiza Oliveira Perucci8Luci Maria SantAna Dusse9Federal University of Minas GeraisFederal University of Minas GeraisFederal University of Minas GeraisFederal University of Minas GeraisVeterinary School, Federal University of Minas GeraisUniversity of SoutamptonFederal University of Ouro PretoFederal University of Minas GeraisFederal University of Ouro PretoFederal University of Minas GeraisObjective: Investigating D-Dimer/D-Di and plasminogen activator inhibitor type-1/PAI-1 levels throughout gestation in women with preeclampsia/PE risk factors. Methods: D-Di and PAI-1 plasma levels were determined in 28 women at 12–19, 20–29, 30–34 and 35–40 weeks of gestation. Results: D-Di was lower at 12–19 weeks and higher at 30–34 weeks in women who developed PE versus who did not develop it. D-Di increased throughout gestation in both groups, peaking earlier in pregnant women who developed PE versus who did not develop it. PA1-1 increased across gestation, but it didn’t differ between groups. Conclusion: D-Di was able to discriminate these groups of women at 12–19 and 30–34 weeks of gestation.http://dx.doi.org/10.1080/10641955.2019.1577435preeclampsiad-dimerpai-1longitudinal studyhypercoagulability |
| spellingShingle | Flávia Campos Lucena Eura Martins Lage Patrícia Gonçalves Teixeira Alexandre Simões Barbosa Rejane Diniz Bashir Lwaleed André Talvani Patrícia Nessralla Alpoim Luiza Oliveira Perucci Luci Maria SantAna Dusse Longitudinal assessment of D-dimer and plasminogen activator inhibitor type-1 plasma levels in pregnant women with risk factors for preeclampsia Hypertension in Pregnancy preeclampsia d-dimer pai-1 longitudinal study hypercoagulability |
| title | Longitudinal assessment of D-dimer and plasminogen activator inhibitor type-1 plasma levels in pregnant women with risk factors for preeclampsia |
| title_full | Longitudinal assessment of D-dimer and plasminogen activator inhibitor type-1 plasma levels in pregnant women with risk factors for preeclampsia |
| title_fullStr | Longitudinal assessment of D-dimer and plasminogen activator inhibitor type-1 plasma levels in pregnant women with risk factors for preeclampsia |
| title_full_unstemmed | Longitudinal assessment of D-dimer and plasminogen activator inhibitor type-1 plasma levels in pregnant women with risk factors for preeclampsia |
| title_short | Longitudinal assessment of D-dimer and plasminogen activator inhibitor type-1 plasma levels in pregnant women with risk factors for preeclampsia |
| title_sort | longitudinal assessment of d dimer and plasminogen activator inhibitor type 1 plasma levels in pregnant women with risk factors for preeclampsia |
| topic | preeclampsia d-dimer pai-1 longitudinal study hypercoagulability |
| url | http://dx.doi.org/10.1080/10641955.2019.1577435 |
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