Aqueductal stenosis secondary to Whipple’s disease

We present a 54-year old male with a history of Whipple’s Disease (WD) diagnosed 21 years previously and proven by an inguinal lymph node biopsy. Antibiotic therapy was initiated upon confirmation of gastrointestinal (GI) involvement via colonoscopy. On the most recent occasion, the patient presente...

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Main Authors: F Chiang, A R Verde, D E Sossa, D G Sossa, M Castillo
Format: Article
Language:English
Published: Ubiquity Press 2013-11-01
Series:Journal of the Belgian Society of Radiology
Online Access:https://www.jbsr.be/articles/527
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author F Chiang
A R Verde
D E Sossa
D G Sossa
M Castillo
author_facet F Chiang
A R Verde
D E Sossa
D G Sossa
M Castillo
author_sort F Chiang
collection DOAJ
description We present a 54-year old male with a history of Whipple’s Disease (WD) diagnosed 21 years previously and proven by an inguinal lymph node biopsy. Antibiotic therapy was initiated upon confirmation of gastrointestinal (GI) involvement via colonoscopy. On the most recent occasion, the patient presented with a 3-week history of ataxic gait, short-term memory loss, incontinence, oculofacial skeletal myorhythmia, and tinnitus. MRI showed markedly enlarged lateral and 3rd ventricles compatible with hydrocephalus. 3D constructive interference in steady state (CISS) images showed a small web traversing the distal cerebral aqueduct with cephalad dilatation (Fig. A). Post contrast images showed enhancement within the stenotic part of the aqueduct (Fig. B).
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spelling doaj.art-edeb7fb5f3374fc8a13ea188de7dd3d42022-12-21T22:08:45ZengUbiquity PressJournal of the Belgian Society of Radiology2514-82812013-11-0196610.5334/jbr-btr.527527Aqueductal stenosis secondary to Whipple’s diseaseF Chiang0A R Verde1D E Sossa2D G Sossa3M Castillo4Department of Radiology, Neuroradiology Division, University of North Carolina at Chapel Hill, Chapel Hill, NC, USADepartment of Radiology, Neuroradiology Division, University of North Carolina at Chapel Hill, Chapel Hill, NC, USADepartment of Radiology, Neuroradiology Division, University of North Carolina at Chapel Hill, Chapel Hill, NC, USADepartment of Radiology, Neuroradiology Division, University of North Carolina at Chapel Hill, Chapel Hill, NC, USADepartment of Radiology, Neuroradiology Division, University of North Carolina at Chapel Hill, Chapel Hill, NC, USAWe present a 54-year old male with a history of Whipple’s Disease (WD) diagnosed 21 years previously and proven by an inguinal lymph node biopsy. Antibiotic therapy was initiated upon confirmation of gastrointestinal (GI) involvement via colonoscopy. On the most recent occasion, the patient presented with a 3-week history of ataxic gait, short-term memory loss, incontinence, oculofacial skeletal myorhythmia, and tinnitus. MRI showed markedly enlarged lateral and 3rd ventricles compatible with hydrocephalus. 3D constructive interference in steady state (CISS) images showed a small web traversing the distal cerebral aqueduct with cephalad dilatation (Fig. A). Post contrast images showed enhancement within the stenotic part of the aqueduct (Fig. B).https://www.jbsr.be/articles/527
spellingShingle F Chiang
A R Verde
D E Sossa
D G Sossa
M Castillo
Aqueductal stenosis secondary to Whipple’s disease
Journal of the Belgian Society of Radiology
title Aqueductal stenosis secondary to Whipple’s disease
title_full Aqueductal stenosis secondary to Whipple’s disease
title_fullStr Aqueductal stenosis secondary to Whipple’s disease
title_full_unstemmed Aqueductal stenosis secondary to Whipple’s disease
title_short Aqueductal stenosis secondary to Whipple’s disease
title_sort aqueductal stenosis secondary to whipple s disease
url https://www.jbsr.be/articles/527
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AT arverde aqueductalstenosissecondarytowhipplesdisease
AT desossa aqueductalstenosissecondarytowhipplesdisease
AT dgsossa aqueductalstenosissecondarytowhipplesdisease
AT mcastillo aqueductalstenosissecondarytowhipplesdisease