Resveratrol modulates miRNA machinery proteins in different types of colon cancer cells
Resveratrol (RSV) is a stilbenoid compound that shows anticancer activity in many cancer cells. Exosomes might affect carcinogenesis and the development of colorectal cancer by affecting communication between tumor cells in the tumor microenvironment via their cargo content miRNA. The aim of this st...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
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De Gruyter
2023-12-01
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Series: | Türk Biyokimya Dergisi |
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Online Access: | https://doi.org/10.1515/tjb-2023-0076 |
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author | Becer Eda Madencioğlu Servet Kabadayı Hilal Vatansever Hafize Seda |
author_facet | Becer Eda Madencioğlu Servet Kabadayı Hilal Vatansever Hafize Seda |
author_sort | Becer Eda |
collection | DOAJ |
description | Resveratrol (RSV) is a stilbenoid compound that shows anticancer activity in many cancer cells. Exosomes might affect carcinogenesis and the development of colorectal cancer by affecting communication between tumor cells in the tumor microenvironment via their cargo content miRNA. The aim of this study is to determine the effect of RSV on the expression of Dicer, Ago2, eIf2α, CD-9, CD-63, and exosomal miRNA levels in COLO320 and COLO741 colon cancer cell lines. |
first_indexed | 2024-03-07T16:21:15Z |
format | Article |
id | doaj.art-edee69cd1c96412b812acf28d9cdb376 |
institution | Directory Open Access Journal |
issn | 1303-829X |
language | English |
last_indexed | 2024-03-07T16:21:15Z |
publishDate | 2023-12-01 |
publisher | De Gruyter |
record_format | Article |
series | Türk Biyokimya Dergisi |
spelling | doaj.art-edee69cd1c96412b812acf28d9cdb3762024-03-04T07:29:49ZengDe GruyterTürk Biyokimya Dergisi1303-829X2023-12-0149111612210.1515/tjb-2023-0076Resveratrol modulates miRNA machinery proteins in different types of colon cancer cellsBecer Eda0Madencioğlu Servet1Kabadayı Hilal2Vatansever Hafize Seda3Faculty of Pharmacy, Eastern Mediterranean University, 99628, Fagamusta, TürkiyeDepartment of Nutrition and Dietetics, Faculty of Health Sciences, Near East University, 99138, Nicosia, North Cyprus via Mersin 10, TürkiyeDepartment of Histology and Embryology, Faculty of Medicine, Manisa Celal Bayar University, Manisa, TürkiyeDESAM Institute, Near East University, Nicosia, TürkiyeResveratrol (RSV) is a stilbenoid compound that shows anticancer activity in many cancer cells. Exosomes might affect carcinogenesis and the development of colorectal cancer by affecting communication between tumor cells in the tumor microenvironment via their cargo content miRNA. The aim of this study is to determine the effect of RSV on the expression of Dicer, Ago2, eIf2α, CD-9, CD-63, and exosomal miRNA levels in COLO320 and COLO741 colon cancer cell lines.https://doi.org/10.1515/tjb-2023-0076resveratrolstilbenesmirnaexosomescolon cancer |
spellingShingle | Becer Eda Madencioğlu Servet Kabadayı Hilal Vatansever Hafize Seda Resveratrol modulates miRNA machinery proteins in different types of colon cancer cells Türk Biyokimya Dergisi resveratrol stilbenes mirna exosomes colon cancer |
title | Resveratrol modulates miRNA machinery proteins in different types of colon cancer cells |
title_full | Resveratrol modulates miRNA machinery proteins in different types of colon cancer cells |
title_fullStr | Resveratrol modulates miRNA machinery proteins in different types of colon cancer cells |
title_full_unstemmed | Resveratrol modulates miRNA machinery proteins in different types of colon cancer cells |
title_short | Resveratrol modulates miRNA machinery proteins in different types of colon cancer cells |
title_sort | resveratrol modulates mirna machinery proteins in different types of colon cancer cells |
topic | resveratrol stilbenes mirna exosomes colon cancer |
url | https://doi.org/10.1515/tjb-2023-0076 |
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