Resveratrol modulates miRNA machinery proteins in different types of colon cancer cells

Resveratrol (RSV) is a stilbenoid compound that shows anticancer activity in many cancer cells. Exosomes might affect carcinogenesis and the development of colorectal cancer by affecting communication between tumor cells in the tumor microenvironment via their cargo content miRNA. The aim of this st...

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Main Authors: Becer Eda, Madencioğlu Servet, Kabadayı Hilal, Vatansever Hafize Seda
Format: Article
Language:English
Published: De Gruyter 2023-12-01
Series:Türk Biyokimya Dergisi
Subjects:
Online Access:https://doi.org/10.1515/tjb-2023-0076
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author Becer Eda
Madencioğlu Servet
Kabadayı Hilal
Vatansever Hafize Seda
author_facet Becer Eda
Madencioğlu Servet
Kabadayı Hilal
Vatansever Hafize Seda
author_sort Becer Eda
collection DOAJ
description Resveratrol (RSV) is a stilbenoid compound that shows anticancer activity in many cancer cells. Exosomes might affect carcinogenesis and the development of colorectal cancer by affecting communication between tumor cells in the tumor microenvironment via their cargo content miRNA. The aim of this study is to determine the effect of RSV on the expression of Dicer, Ago2, eIf2α, CD-9, CD-63, and exosomal miRNA levels in COLO320 and COLO741 colon cancer cell lines.
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spelling doaj.art-edee69cd1c96412b812acf28d9cdb3762024-03-04T07:29:49ZengDe GruyterTürk Biyokimya Dergisi1303-829X2023-12-0149111612210.1515/tjb-2023-0076Resveratrol modulates miRNA machinery proteins in different types of colon cancer cellsBecer Eda0Madencioğlu Servet1Kabadayı Hilal2Vatansever Hafize Seda3Faculty of Pharmacy, Eastern Mediterranean University, 99628, Fagamusta, TürkiyeDepartment of Nutrition and Dietetics, Faculty of Health Sciences, Near East University, 99138, Nicosia, North Cyprus via Mersin 10, TürkiyeDepartment of Histology and Embryology, Faculty of Medicine, Manisa Celal Bayar University, Manisa, TürkiyeDESAM Institute, Near East University, Nicosia, TürkiyeResveratrol (RSV) is a stilbenoid compound that shows anticancer activity in many cancer cells. Exosomes might affect carcinogenesis and the development of colorectal cancer by affecting communication between tumor cells in the tumor microenvironment via their cargo content miRNA. The aim of this study is to determine the effect of RSV on the expression of Dicer, Ago2, eIf2α, CD-9, CD-63, and exosomal miRNA levels in COLO320 and COLO741 colon cancer cell lines.https://doi.org/10.1515/tjb-2023-0076resveratrolstilbenesmirnaexosomescolon cancer
spellingShingle Becer Eda
Madencioğlu Servet
Kabadayı Hilal
Vatansever Hafize Seda
Resveratrol modulates miRNA machinery proteins in different types of colon cancer cells
Türk Biyokimya Dergisi
resveratrol
stilbenes
mirna
exosomes
colon cancer
title Resveratrol modulates miRNA machinery proteins in different types of colon cancer cells
title_full Resveratrol modulates miRNA machinery proteins in different types of colon cancer cells
title_fullStr Resveratrol modulates miRNA machinery proteins in different types of colon cancer cells
title_full_unstemmed Resveratrol modulates miRNA machinery proteins in different types of colon cancer cells
title_short Resveratrol modulates miRNA machinery proteins in different types of colon cancer cells
title_sort resveratrol modulates mirna machinery proteins in different types of colon cancer cells
topic resveratrol
stilbenes
mirna
exosomes
colon cancer
url https://doi.org/10.1515/tjb-2023-0076
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AT madenciogluservet resveratrolmodulatesmirnamachineryproteinsindifferenttypesofcoloncancercells
AT kabadayıhilal resveratrolmodulatesmirnamachineryproteinsindifferenttypesofcoloncancercells
AT vatanseverhafizeseda resveratrolmodulatesmirnamachineryproteinsindifferenttypesofcoloncancercells