In Silico Modeling of the Interaction of NBD Steroids with Insect Steroid-Binding Protein SPC-2

In Silico Modeling of the Interaction of NBD Steroids with Insect Steroid-Binding Protein SPC-2

Two fluorescent sterol-like molecules have been synthesized, namely, a derivative of 7-nitrobenzofurazan (NBD) with 17-(methylamino)-androst-5-en-3beta-ol (DAM-NBD) and NBD-piperazine conjugate with cholesteryl chloroformate (NBD-pip-CCF). In silico docking and plasma membrane simulations have shown...

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Bibliographic Details
Main Authors: Hleb Pozniak, Anna Stoliarchuk, Yaroslav Faletrov, Vladimir Shkumatov
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Chemistry Proceedings
Subjects:
4-chloro-7-nitrobenzofurazan (NBD-Cl)
molecular docking
fluorescence
cholesterol
Online Access:https://www.mdpi.com/2673-4583/12/1/86

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