INTERACTIONS BETWEEN HYALURONAN AND ITS RECEPTORS (CD44, RHAMM) REGULATE THE ACTIVITIES OF INFLAMMATION AND CANCER

INTERACTIONS BETWEEN HYALURONAN AND ITS RECEPTORS (CD44, RHAMM) REGULATE THE ACTIVITIES OF INFLAMMATION AND CANCER

The glycosaminoglycan hyaluronan (HA), a major component of extracellular matrices (ECMs), and cell surface receptors of HA have been proposed to have pivotal roles in cell proliferation, migration, and invasion, which are necessary for inflammation and cancer progression. CD44 and RHAMM (receptor o...

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Bibliographic Details
Main Authors: SUNITI eMISRA, Roger R. Markwald, Vincent C. Hascall, Shibnath eGhatak
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-05-01
Series:Frontiers in Immunology
Subjects:
Inflammation
Cancer
CD44
hyaluronan
RHAMM
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00201/full

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