Genetic Variation in Complex Traits in Transgenic α-Synuclein Strains of <i>Caenorhabditis elegans</i>
Different genetic backgrounds can modify the effect of mutated genes. Human α-synuclein (<i>SNCA</i>) gene encodes α-synuclein, and its oligomeric complexes accumulate with age and mediate the disruption of cellular homeostasis, resulting in the neuronal death that is characteristic of P...
Main Authors: | Yiru A. Wang, Lisa van Sluijs, Yu Nie, Mark G. Sterken, Simon C. Harvey, Jan E. Kammenga |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-07-01
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Series: | Genes |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4425/11/7/778 |
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