Gene Therapy Advances: A Meta-Analysis of AAV Usage in Clinical Settings

Adeno-associated viruses (AAVs) are the safest and most effective gene delivery vehicles to drive long-term transgene expression in gene therapy. While animal studies have shown promising results, the translatability of AAVs into clinical settings has been partly limited due to their restricted gene...

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Bibliographic Details
Main Authors: Hau Kiu Edna Au, Mark Isalan, Michal Mielcarek
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Medicine
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2021.809118/full