Postoperative permanent section evaluation of Mohs micrographic surgery debulk specimens does not result in upstaging of cutaneous squamous cell carcinoma compared to stage at the completion of surgery: A retrospective case seriesCapsule Summary
Background: Mohs micrographic surgery (MMS) is used for the treatment of high-risk cutaneous squamous cell carcinoma (cSCC). MMS examines the surgical margins in real time and does not commonly examine the central component of the tumor. Objective: To determine if debulk specimens provide additional...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2024-06-01
|
| Series: | JAAD International |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666328724000142 |
| _version_ | 1827237588941930496 |
|---|---|
| author | Andrea Gilmore, MD Brianna Castillo, MD Nicholas Golda, MD Kara Braudis, MD Emily Smith, MD |
| author_facet | Andrea Gilmore, MD Brianna Castillo, MD Nicholas Golda, MD Kara Braudis, MD Emily Smith, MD |
| author_sort | Andrea Gilmore, MD |
| collection | DOAJ |
| description | Background: Mohs micrographic surgery (MMS) is used for the treatment of high-risk cutaneous squamous cell carcinoma (cSCC). MMS examines the surgical margins in real time and does not commonly examine the central component of the tumor. Objective: To determine if debulk specimens provide additional details relevant to tumor staging not gained from routine MMS. Methods: A retrospective chart review of debulk specimens taken during MMS for cSCC was performed. Dermatopathology reports were analyzed and tumors were staged using Brigham and Women’s Hospital and American Joint Committee on Cancer’s 8th edition staging systems. Results: Permanent section evaluation of debulk specimens did not result in clinically meaningful information for staging that could not be gained from MMS layers or initial biopsy analysis. Limitations: A single institution, and a small sample size of 39 tumors. Conclusions: Evaluation of debulk specimens during MMS may not always be an effective use of time or health care resources. |
| first_indexed | 2024-04-25T00:46:56Z |
| format | Article |
| id | doaj.art-edfd386fde4a4d07a7604f755cabe3d4 |
| institution | Directory Open Access Journal |
| issn | 2666-3287 |
| language | English |
| last_indexed | 2025-03-21T20:39:18Z |
| publishDate | 2024-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | JAAD International |
| spelling | doaj.art-edfd386fde4a4d07a7604f755cabe3d42024-06-01T04:23:27ZengElsevierJAAD International2666-32872024-06-0115100104Postoperative permanent section evaluation of Mohs micrographic surgery debulk specimens does not result in upstaging of cutaneous squamous cell carcinoma compared to stage at the completion of surgery: A retrospective case seriesCapsule SummaryAndrea Gilmore, MD0Brianna Castillo, MD1Nicholas Golda, MD2Kara Braudis, MD3Emily Smith, MD4Department of Dermatology, University of Missouri Columbia, Columbia, Missouri; Correspondence to: Andrea Gilmore, MD, Department of Dermatology, University of Missouri Columbia, 1 Hospital Drive, MA111, Columbia, MO, 65212.Department of Dermatology, University of Arizona, Tuscon, ArizonaUS Dermatology Partners, Lee’s Summit, MissouriDepartment of Dermatology, University of Missouri Columbia, Columbia, MissouriDepartment of Dermatology, Saint Louis University, St. Louis, MissouriBackground: Mohs micrographic surgery (MMS) is used for the treatment of high-risk cutaneous squamous cell carcinoma (cSCC). MMS examines the surgical margins in real time and does not commonly examine the central component of the tumor. Objective: To determine if debulk specimens provide additional details relevant to tumor staging not gained from routine MMS. Methods: A retrospective chart review of debulk specimens taken during MMS for cSCC was performed. Dermatopathology reports were analyzed and tumors were staged using Brigham and Women’s Hospital and American Joint Committee on Cancer’s 8th edition staging systems. Results: Permanent section evaluation of debulk specimens did not result in clinically meaningful information for staging that could not be gained from MMS layers or initial biopsy analysis. Limitations: A single institution, and a small sample size of 39 tumors. Conclusions: Evaluation of debulk specimens during MMS may not always be an effective use of time or health care resources.http://www.sciencedirect.com/science/article/pii/S2666328724000142dermatopathology(high-risk) squamous cell carcinomaMohs micrographic surgery |
| spellingShingle | Andrea Gilmore, MD Brianna Castillo, MD Nicholas Golda, MD Kara Braudis, MD Emily Smith, MD Postoperative permanent section evaluation of Mohs micrographic surgery debulk specimens does not result in upstaging of cutaneous squamous cell carcinoma compared to stage at the completion of surgery: A retrospective case seriesCapsule Summary JAAD International dermatopathology (high-risk) squamous cell carcinoma Mohs micrographic surgery |
| title | Postoperative permanent section evaluation of Mohs micrographic surgery debulk specimens does not result in upstaging of cutaneous squamous cell carcinoma compared to stage at the completion of surgery: A retrospective case seriesCapsule Summary |
| title_full | Postoperative permanent section evaluation of Mohs micrographic surgery debulk specimens does not result in upstaging of cutaneous squamous cell carcinoma compared to stage at the completion of surgery: A retrospective case seriesCapsule Summary |
| title_fullStr | Postoperative permanent section evaluation of Mohs micrographic surgery debulk specimens does not result in upstaging of cutaneous squamous cell carcinoma compared to stage at the completion of surgery: A retrospective case seriesCapsule Summary |
| title_full_unstemmed | Postoperative permanent section evaluation of Mohs micrographic surgery debulk specimens does not result in upstaging of cutaneous squamous cell carcinoma compared to stage at the completion of surgery: A retrospective case seriesCapsule Summary |
| title_short | Postoperative permanent section evaluation of Mohs micrographic surgery debulk specimens does not result in upstaging of cutaneous squamous cell carcinoma compared to stage at the completion of surgery: A retrospective case seriesCapsule Summary |
| title_sort | postoperative permanent section evaluation of mohs micrographic surgery debulk specimens does not result in upstaging of cutaneous squamous cell carcinoma compared to stage at the completion of surgery a retrospective case seriescapsule summary |
| topic | dermatopathology (high-risk) squamous cell carcinoma Mohs micrographic surgery |
| url | http://www.sciencedirect.com/science/article/pii/S2666328724000142 |
| work_keys_str_mv | AT andreagilmoremd postoperativepermanentsectionevaluationofmohsmicrographicsurgerydebulkspecimensdoesnotresultinupstagingofcutaneoussquamouscellcarcinomacomparedtostageatthecompletionofsurgeryaretrospectivecaseseriescapsulesummary AT briannacastillomd postoperativepermanentsectionevaluationofmohsmicrographicsurgerydebulkspecimensdoesnotresultinupstagingofcutaneoussquamouscellcarcinomacomparedtostageatthecompletionofsurgeryaretrospectivecaseseriescapsulesummary AT nicholasgoldamd postoperativepermanentsectionevaluationofmohsmicrographicsurgerydebulkspecimensdoesnotresultinupstagingofcutaneoussquamouscellcarcinomacomparedtostageatthecompletionofsurgeryaretrospectivecaseseriescapsulesummary AT karabraudismd postoperativepermanentsectionevaluationofmohsmicrographicsurgerydebulkspecimensdoesnotresultinupstagingofcutaneoussquamouscellcarcinomacomparedtostageatthecompletionofsurgeryaretrospectivecaseseriescapsulesummary AT emilysmithmd postoperativepermanentsectionevaluationofmohsmicrographicsurgerydebulkspecimensdoesnotresultinupstagingofcutaneoussquamouscellcarcinomacomparedtostageatthecompletionofsurgeryaretrospectivecaseseriescapsulesummary |