Proteomic analysis reveals that cigarette smoke exposure diminishes ovarian reserve in mice by disrupting the CREB1-mediated ovarian granulosa cell proliferation-apoptosis balance

Proteomic analysis reveals that cigarette smoke exposure diminishes ovarian reserve in mice by disrupting the CREB1-mediated ovarian granulosa cell proliferation-apoptosis balance

Exposure to cigarette smoke (CS) adversely affects ovarian health and it is currently unknown how CS exposure causes ovarian injury. This study compared the differences in proteomics between CS exposure and healthy control groups using liquid chromatography-tandem mass spectrometry quantitative prot...

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Bibliographic Details
Main Authors: Mengting Xu, Fang Li, XiaoYan Xu, Nengyin Hu, Jianing Miao, Yanhui Zhao, Sailing Ji, Ying Wang, Lili Wang
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Proteomics
Premature ovarian insufficiency
Cigarette smoke exposure
Granulosa cell
CREB1
Proliferation-apoptosis balance
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651324000642

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