Novel small molecule protein kinase CK2 inhibitors exert potent antitumor effects on T98G and SEGA cells in vitro

Novel small molecule protein kinase CK2 inhibitors exert potent antitumor effects on T98G and SEGA cells in vitro

Tumours of astroglial origin, both malignant glioblastoma (GBM) and benign subependymal giant cell astrocytoma (SEGA), pose a serious medical problem. Casein kinase 2 (CK2), a member of the serine/threonine kinase family, has antiapoptotic properties and plays a vital role in glial tumour cell survi...

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Bibliographic Details
Main Authors: Emanuela Pucko, Robert Ostrowski, Ewa Matyja
Format: Article
Language:English
Published: Termedia Publishing House 2019-09-01
Series:Folia Neuropathologica
Subjects:
casein kinase inhibitors
ck2
antitumor activity
glioma cell lines
glioblastoma
Online Access:https://www.termedia.pl/Novel-small-molecule-protein-kinase-CK2-inhibitors-exert-potent-antitumor-effects-on-T98G-and-SEGA-cells-in-vitro,20,37901,1,1.html

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