NMR Detection of Isomers Arising from Restricted Rotation of the C-N Amide Bond of N-Formyl-o-toluidine and N,N’-bis-Formyl-o-tolidine
Full and unambiguous assignment of all 1H- and 13C-NMR resonances of the isomers due to restricted C-N amide bond rotation of N-formyl-o-toluidine and N,N'-bis-formyl-o-tolidine in DMSO-d6 is reported. The cis-isomer predominates in the equilibrium mixture of both compounds as 1D-NOE difference...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2002-08-01
|
| Series: | Molecules |
| Subjects: | |
| Online Access: | http://www.mdpi.com/1420-3049/7/8/662/ |
| _version_ | 1818479626360455168 |
|---|---|
| author | NoemàWaksman Ricardo Gómez-Flores Reyes Tamez-Guerra Cristina RodrÃÂguez-Padilla Adolfo Caballero-Quintero Juan F. Colunga-Valladares Ramiro Quintanilla-Licea |
| author_facet | NoemàWaksman Ricardo Gómez-Flores Reyes Tamez-Guerra Cristina RodrÃÂguez-Padilla Adolfo Caballero-Quintero Juan F. Colunga-Valladares Ramiro Quintanilla-Licea |
| author_sort | NoemàWaksman |
| collection | DOAJ |
| description | Full and unambiguous assignment of all 1H- and 13C-NMR resonances of the isomers due to restricted C-N amide bond rotation of N-formyl-o-toluidine and N,N'-bis-formyl-o-tolidine in DMSO-d6 is reported. The cis-isomer predominates in the equilibrium mixture of both compounds as 1D-NOE difference experiments show. |
| first_indexed | 2024-12-10T11:13:15Z |
| format | Article |
| id | doaj.art-ee07f44598694393854b2ca64d8302f6 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-12-10T11:13:15Z |
| publishDate | 2002-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-ee07f44598694393854b2ca64d8302f62022-12-22T01:51:20ZengMDPI AGMolecules1420-30492002-08-017866267310.3390/70800662NMR Detection of Isomers Arising from Restricted Rotation of the C-N Amide Bond of N-Formyl-o-toluidine and N,N’-bis-Formyl-o-tolidineNoemàWaksmanRicardo Gómez-FloresReyes Tamez-GuerraCristina RodrÃÂguez-PadillaAdolfo Caballero-QuinteroJuan F. Colunga-ValladaresRamiro Quintanilla-LiceaFull and unambiguous assignment of all 1H- and 13C-NMR resonances of the isomers due to restricted C-N amide bond rotation of N-formyl-o-toluidine and N,N'-bis-formyl-o-tolidine in DMSO-d6 is reported. The cis-isomer predominates in the equilibrium mixture of both compounds as 1D-NOE difference experiments show.http://www.mdpi.com/1420-3049/7/8/662/Amide bondrestricted rotation1H-NMR13C-NMRNOE |
| spellingShingle | NoemàWaksman Ricardo Gómez-Flores Reyes Tamez-Guerra Cristina RodrÃÂguez-Padilla Adolfo Caballero-Quintero Juan F. Colunga-Valladares Ramiro Quintanilla-Licea NMR Detection of Isomers Arising from Restricted Rotation of the C-N Amide Bond of N-Formyl-o-toluidine and N,N’-bis-Formyl-o-tolidine Molecules Amide bond restricted rotation 1H-NMR 13C-NMR NOE |
| title | NMR Detection of Isomers Arising from Restricted Rotation of the C-N Amide Bond of N-Formyl-o-toluidine and N,N’-bis-Formyl-o-tolidine |
| title_full | NMR Detection of Isomers Arising from Restricted Rotation of the C-N Amide Bond of N-Formyl-o-toluidine and N,N’-bis-Formyl-o-tolidine |
| title_fullStr | NMR Detection of Isomers Arising from Restricted Rotation of the C-N Amide Bond of N-Formyl-o-toluidine and N,N’-bis-Formyl-o-tolidine |
| title_full_unstemmed | NMR Detection of Isomers Arising from Restricted Rotation of the C-N Amide Bond of N-Formyl-o-toluidine and N,N’-bis-Formyl-o-tolidine |
| title_short | NMR Detection of Isomers Arising from Restricted Rotation of the C-N Amide Bond of N-Formyl-o-toluidine and N,N’-bis-Formyl-o-tolidine |
| title_sort | nmr detection of isomers arising from restricted rotation of the c n amide bond of n formyl o toluidine and n na¢a€a™ bis formyl o tolidine |
| topic | Amide bond restricted rotation 1H-NMR 13C-NMR NOE |
| url | http://www.mdpi.com/1420-3049/7/8/662/ |
| work_keys_str_mv | AT noemaƒawaksman nmrdetectionofisomersarisingfromrestrictedrotationofthecnamidebondofnformylotoluidineandnnaaabisformylotolidine AT ricardogaƒa3mezflores nmrdetectionofisomersarisingfromrestrictedrotationofthecnamidebondofnformylotoluidineandnnaaabisformylotolidine AT reyestamezguerra nmrdetectionofisomersarisingfromrestrictedrotationofthecnamidebondofnformylotoluidineandnnaaabisformylotolidine AT cristinarodraƒaguezpadilla nmrdetectionofisomersarisingfromrestrictedrotationofthecnamidebondofnformylotoluidineandnnaaabisformylotolidine AT adolfocaballeroquintero nmrdetectionofisomersarisingfromrestrictedrotationofthecnamidebondofnformylotoluidineandnnaaabisformylotolidine AT juanfcolungavalladares nmrdetectionofisomersarisingfromrestrictedrotationofthecnamidebondofnformylotoluidineandnnaaabisformylotolidine AT ramiroquintanillalicea nmrdetectionofisomersarisingfromrestrictedrotationofthecnamidebondofnformylotoluidineandnnaaabisformylotolidine |