Apolipoprotein E, a Gene with Complex Biological Interactions in the Aging Brain

Age-dependent neurodegeneration in Alzheimer disease (AD) may be viewed as a complex interaction among: (i) susceptibility polymorphisms, (ii) somatic mutations or alterations that occur over extended periods of time, and (iii) environmental interactions. Putative “sporadic” diseases appear to have...

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Bibliografische gegevens
Hoofdauteur: Allen D. Roses
Formaat: Artikel
Taal:English
Gepubliceerd in: Elsevier 1997-01-01
Reeks:Neurobiology of Disease
Online toegang:http://www.sciencedirect.com/science/article/pii/S0969996197901613