Unification of Cas protein families and a simple scenario for the origin and evolution of CRISPR-Cas systems

Unification of Cas protein families and a simple scenario for the origin and evolution of CRISPR-Cas systems

<p>Abstract</p> <p>Background</p> <p>The CRISPR-Cas adaptive immunity systems that are present in most Archaea and many Bacteria function by incorporating fragments of alien genomes into specific genomic loci, transcribing the inserts and using the transcripts as guide...

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Bibliographic Details
Main Authors: Wolf Yuri I, Aravind L, Makarova Kira S, Koonin Eugene V
Format: Article
Language:English
Published: BMC 2011-07-01
Series:Biology Direct
Online Access:http://www.biology-direct.com/content/6/1/38

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