Neocortical inhibitory interneuron subtypes are differentially attuned to synchrony- and rate-coded information
In order to address whether distinct subtypes of neurons are more sensitive to information carried by synchrony versus rate, Prince et al. used optical stimulation in slices of somatosensory cortex from mouse lines labelling fast-spiking (FS) and regular-spiking (RS) interneurons. They demonstrated...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2021-08-01
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| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-021-02437-y |
| _version_ | 1818421035878318080 |
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| author | Luke Y. Prince Matthew M. Tran Dorian Grey Lydia Saad Helen Chasiotis Jeehyun Kwag Michael M. Kohl Blake A. Richards |
| author_facet | Luke Y. Prince Matthew M. Tran Dorian Grey Lydia Saad Helen Chasiotis Jeehyun Kwag Michael M. Kohl Blake A. Richards |
| author_sort | Luke Y. Prince |
| collection | DOAJ |
| description | In order to address whether distinct subtypes of neurons are more sensitive to information carried by synchrony versus rate, Prince et al. used optical stimulation in slices of somatosensory cortex from mouse lines labelling fast-spiking (FS) and regular-spiking (RS) interneurons. They demonstrated that FS and RS interneurons had differential sensitivity to changes in synchrony and rate, which advances our understanding of neural processing in the neocortex. |
| first_indexed | 2024-12-14T13:03:58Z |
| format | Article |
| id | doaj.art-ee0eb814510845bd974628b6e520e8f3 |
| institution | Directory Open Access Journal |
| issn | 2399-3642 |
| language | English |
| last_indexed | 2024-12-14T13:03:58Z |
| publishDate | 2021-08-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Communications Biology |
| spelling | doaj.art-ee0eb814510845bd974628b6e520e8f32022-12-21T23:00:21ZengNature PortfolioCommunications Biology2399-36422021-08-014111610.1038/s42003-021-02437-yNeocortical inhibitory interneuron subtypes are differentially attuned to synchrony- and rate-coded informationLuke Y. Prince0Matthew M. Tran1Dorian Grey2Lydia Saad3Helen Chasiotis4Jeehyun Kwag5Michael M. Kohl6Blake A. Richards7Mila - Quebec Artificial Intelligence InstituteDepartment of Biological Sciences, University of Toronto ScarboroughDepartment of Biological Sciences, University of Toronto ScarboroughDepartment of Biological Sciences, University of Toronto ScarboroughDepartment of Biological Sciences, University of Toronto ScarboroughDepartment of Brain and Cognitive Engineering, Korea UniversityInstitute of Neuroscience and Psychology, University of GlasgowMila - Quebec Artificial Intelligence InstituteIn order to address whether distinct subtypes of neurons are more sensitive to information carried by synchrony versus rate, Prince et al. used optical stimulation in slices of somatosensory cortex from mouse lines labelling fast-spiking (FS) and regular-spiking (RS) interneurons. They demonstrated that FS and RS interneurons had differential sensitivity to changes in synchrony and rate, which advances our understanding of neural processing in the neocortex.https://doi.org/10.1038/s42003-021-02437-y |
| spellingShingle | Luke Y. Prince Matthew M. Tran Dorian Grey Lydia Saad Helen Chasiotis Jeehyun Kwag Michael M. Kohl Blake A. Richards Neocortical inhibitory interneuron subtypes are differentially attuned to synchrony- and rate-coded information Communications Biology |
| title | Neocortical inhibitory interneuron subtypes are differentially attuned to synchrony- and rate-coded information |
| title_full | Neocortical inhibitory interneuron subtypes are differentially attuned to synchrony- and rate-coded information |
| title_fullStr | Neocortical inhibitory interneuron subtypes are differentially attuned to synchrony- and rate-coded information |
| title_full_unstemmed | Neocortical inhibitory interneuron subtypes are differentially attuned to synchrony- and rate-coded information |
| title_short | Neocortical inhibitory interneuron subtypes are differentially attuned to synchrony- and rate-coded information |
| title_sort | neocortical inhibitory interneuron subtypes are differentially attuned to synchrony and rate coded information |
| url | https://doi.org/10.1038/s42003-021-02437-y |
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