Frailty impacts immune responses to Moderna COVID-19 mRNA vaccine in older adults

Frailty impacts immune responses to Moderna COVID-19 mRNA vaccine in older adults

Abstract Background Immune responses to COVID-19 mRNA vaccines have not been well characterized in frail older adults. We postulated that frailty is associated with impaired antibody and cellular mRNA vaccine responses. Methods We followed older adults in a retirement facility with longitudinal clin...

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Bibliographic Details
Main Authors: Charles T. Semelka, Michael E. DeWitt, Maria W. Blevins, Beth C. Holbrook, John W. Sanders, Martha A. Alexander-Miller
Format: Article
Language:English
Published: BMC 2023-01-01
Series:Immunity & Ageing
Subjects:
Frailty
Immune function
COVID-19
Online Access:https://doi.org/10.1186/s12979-023-00327-x

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