In Vitro Phenotypic Activity and In Silico Analysis of Natural Products from Brazilian Biodiversity on <i>Trypanosoma cruzi</i>

In Vitro Phenotypic Activity and In Silico Analysis of Natural Products from Brazilian Biodiversity on <i>Trypanosoma cruzi</i>

Chagas disease (CD) affects more than 6 million people worldwide. The available treatment is far from ideal, creating a demand for new alternative therapies. Botanical diversity provides a wide range of novel potential therapeutic scaffolds. Presently, our aim was to evaluate the mammalian host toxi...

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Bibliographic Details
Main Authors: Raiza B. Peres, Ludmila F. de A. Fiuza, Patrícia B. da Silva, Marcos M. Batista, Flávia da C. Camillo, André M. Marques, Lavínia de C. Brito, Maria R. Figueiredo, Maria de N. C. Soeiro
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Molecules
Subjects:
<i>T. cruzi</i>
Chagas diseases
natural products
withanolides
aurelianolides
in silico ADMET
Online Access:https://www.mdpi.com/1420-3049/26/18/5676

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