The microbiome and gastric carcinogenesis
Gastric cancer occurs in a small group of patients following chronic infection with Helicobacter pylori. The development of gastric cancer is multifactorial. Current knowledge that a complex microbial community inhabits the stomach has raised the hypothesis that bacteria other than H. pylori may pla...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Verduci Editore
2020-01-01
|
| Series: | Microbiota in Health and Disease |
| Subjects: | |
| Online Access: | https://www.microbiotajournal.com/wp-content/uploads/sites/7/2020/01/e191-The-microbiome-and-gastric-carcinogenesis.pdf |
| _version_ | 1831545265820008448 |
|---|---|
| author | J. Pereira-Marques C. Schulz K. Schütte C. Figueiredo |
| author_facet | J. Pereira-Marques C. Schulz K. Schütte C. Figueiredo |
| author_sort | J. Pereira-Marques |
| collection | DOAJ |
| description | Gastric cancer occurs in a small group of patients following chronic infection with Helicobacter pylori. The development of gastric cancer is multifactorial. Current knowledge that a complex microbial community inhabits the stomach has raised the hypothesis that bacteria other than H. pylori may play a role in gastric carcinogenesis. In this paper, we summarize recent results of the characterization of the microbiota at different sites of the gastrointestinal tract, including the stomach. We also review the latest evidence from human studies and from animal models addressing the role of the gastric microbiota in gastric carcinogenesis. Finally, we highlight recent reports that explore the oral and the gut microbiota as potential gastric cancer biomarkers. |
| first_indexed | 2024-12-17T01:24:27Z |
| format | Article |
| id | doaj.art-ee1cf9847cd3485a8213e4fc5287cbb4 |
| institution | Directory Open Access Journal |
| issn | 2704-8845 |
| language | English |
| last_indexed | 2024-12-17T01:24:27Z |
| publishDate | 2020-01-01 |
| publisher | Verduci Editore |
| record_format | Article |
| series | Microbiota in Health and Disease |
| spelling | doaj.art-ee1cf9847cd3485a8213e4fc5287cbb42022-12-21T22:08:44ZengVerduci EditoreMicrobiota in Health and Disease2704-88452020-01-01210.26355/mhd_20201_191191The microbiome and gastric carcinogenesisJ. Pereira-Marques0C. Schulz1K. Schütte2C. Figueiredo3i3S – Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, PortugalDepartment of Medicine II, University Hospital, LMU Munich, Munich, GermanyDepartment of Internal Medicine and Gastroenterology, Niels-Stensen-Kliniken, Marienhospital Osnabrück, Osnabrück, Germanyi3S – Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, PortugalGastric cancer occurs in a small group of patients following chronic infection with Helicobacter pylori. The development of gastric cancer is multifactorial. Current knowledge that a complex microbial community inhabits the stomach has raised the hypothesis that bacteria other than H. pylori may play a role in gastric carcinogenesis. In this paper, we summarize recent results of the characterization of the microbiota at different sites of the gastrointestinal tract, including the stomach. We also review the latest evidence from human studies and from animal models addressing the role of the gastric microbiota in gastric carcinogenesis. Finally, we highlight recent reports that explore the oral and the gut microbiota as potential gastric cancer biomarkers.https://www.microbiotajournal.com/wp-content/uploads/sites/7/2020/01/e191-The-microbiome-and-gastric-carcinogenesis.pdfmicrobiomegastric cancerstomachgastrointestinal tracthelicobacter pylori. |
| spellingShingle | J. Pereira-Marques C. Schulz K. Schütte C. Figueiredo The microbiome and gastric carcinogenesis Microbiota in Health and Disease microbiome gastric cancer stomach gastrointestinal tract helicobacter pylori. |
| title | The microbiome and gastric carcinogenesis |
| title_full | The microbiome and gastric carcinogenesis |
| title_fullStr | The microbiome and gastric carcinogenesis |
| title_full_unstemmed | The microbiome and gastric carcinogenesis |
| title_short | The microbiome and gastric carcinogenesis |
| title_sort | microbiome and gastric carcinogenesis |
| topic | microbiome gastric cancer stomach gastrointestinal tract helicobacter pylori. |
| url | https://www.microbiotajournal.com/wp-content/uploads/sites/7/2020/01/e191-The-microbiome-and-gastric-carcinogenesis.pdf |
| work_keys_str_mv | AT jpereiramarques themicrobiomeandgastriccarcinogenesis AT cschulz themicrobiomeandgastriccarcinogenesis AT kschutte themicrobiomeandgastriccarcinogenesis AT cfigueiredo themicrobiomeandgastriccarcinogenesis AT jpereiramarques microbiomeandgastriccarcinogenesis AT cschulz microbiomeandgastriccarcinogenesis AT kschutte microbiomeandgastriccarcinogenesis AT cfigueiredo microbiomeandgastriccarcinogenesis |