Susceptibility pattern of enterococci at tertiary care hospital
The study was aimed to characterize enterococci from various clinical specimens, to determine the antimicrobial susceptibility pattern, and to explore the association between virulence factors and antimicrobial resistance. A total of 283 clinical enterococcal isolates were speciated and subjected to...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2017-01-01
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| Series: | Journal of Global Infectious Diseases |
| Subjects: | |
| Online Access: | http://www.jgid.org/article.asp?issn=0974-777X;year=2017;volume=9;issue=2;spage=73;epage=75;aulast=Sachan |
| _version_ | 1818289842691244032 |
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| author | Sadhana Sachan Vinita Rawat Umesh Mukesh Kumar Tripta Kaur Preeti Chaturvedi |
| author_facet | Sadhana Sachan Vinita Rawat Umesh Mukesh Kumar Tripta Kaur Preeti Chaturvedi |
| author_sort | Sadhana Sachan |
| collection | DOAJ |
| description | The study was aimed to characterize enterococci from various clinical specimens, to determine the antimicrobial susceptibility pattern, and to explore the association between virulence factors and antimicrobial resistance. A total of 283 clinical enterococcal isolates were speciated and subjected to antimicrobial susceptibility testing. Virulence factors (hemolysin, gelatinase, and biofilm production) were detected phenotypically. Of the 283 enterococci isolated, 12 species were identified; predominant species were Enterococcus faecalis (82.33%). High-level gentamicin (HLG) and vancomycin resistance were observed among 55.57% and 6.01% of enteroccal isolates, respectively. All vancomycin-resistant enterococci (VREs) were E. faecalis and had VanA phenotype and genotype. Hemolysin, gelatinase, and biofilm production were seen in 15.90%, 12.36%, and 13.43% of enterococcal isolates, respectively. Vancomycin and HLG resistance were observed in 0.35% and 61.86% of the enterococcal isolates producing virulence factors. Isolates resistant to HLG but susceptible to vancomycin expressed more virulent factors. Further research is required to reveal the complex interplay between drug resistance and virulence factors. |
| first_indexed | 2024-12-13T02:18:42Z |
| format | Article |
| id | doaj.art-ee1f04b7535c4f69bc754db9367a9798 |
| institution | Directory Open Access Journal |
| issn | 0974-777X |
| language | English |
| last_indexed | 2024-12-13T02:18:42Z |
| publishDate | 2017-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Global Infectious Diseases |
| spelling | doaj.art-ee1f04b7535c4f69bc754db9367a97982022-12-22T00:02:50ZengWolters Kluwer Medknow PublicationsJournal of Global Infectious Diseases0974-777X2017-01-0192737510.4103/0974-777X.194371Susceptibility pattern of enterococci at tertiary care hospitalSadhana SachanVinita RawatUmeshMukesh KumarTripta KaurPreeti ChaturvediThe study was aimed to characterize enterococci from various clinical specimens, to determine the antimicrobial susceptibility pattern, and to explore the association between virulence factors and antimicrobial resistance. A total of 283 clinical enterococcal isolates were speciated and subjected to antimicrobial susceptibility testing. Virulence factors (hemolysin, gelatinase, and biofilm production) were detected phenotypically. Of the 283 enterococci isolated, 12 species were identified; predominant species were Enterococcus faecalis (82.33%). High-level gentamicin (HLG) and vancomycin resistance were observed among 55.57% and 6.01% of enteroccal isolates, respectively. All vancomycin-resistant enterococci (VREs) were E. faecalis and had VanA phenotype and genotype. Hemolysin, gelatinase, and biofilm production were seen in 15.90%, 12.36%, and 13.43% of enterococcal isolates, respectively. Vancomycin and HLG resistance were observed in 0.35% and 61.86% of the enterococcal isolates producing virulence factors. Isolates resistant to HLG but susceptible to vancomycin expressed more virulent factors. Further research is required to reveal the complex interplay between drug resistance and virulence factors.http://www.jgid.org/article.asp?issn=0974-777X;year=2017;volume=9;issue=2;spage=73;epage=75;aulast=SachanEnterococcusvancomycin resistantvirulence factors |
| spellingShingle | Sadhana Sachan Vinita Rawat Umesh Mukesh Kumar Tripta Kaur Preeti Chaturvedi Susceptibility pattern of enterococci at tertiary care hospital Journal of Global Infectious Diseases Enterococcus vancomycin resistant virulence factors |
| title | Susceptibility pattern of enterococci at tertiary care hospital |
| title_full | Susceptibility pattern of enterococci at tertiary care hospital |
| title_fullStr | Susceptibility pattern of enterococci at tertiary care hospital |
| title_full_unstemmed | Susceptibility pattern of enterococci at tertiary care hospital |
| title_short | Susceptibility pattern of enterococci at tertiary care hospital |
| title_sort | susceptibility pattern of enterococci at tertiary care hospital |
| topic | Enterococcus vancomycin resistant virulence factors |
| url | http://www.jgid.org/article.asp?issn=0974-777X;year=2017;volume=9;issue=2;spage=73;epage=75;aulast=Sachan |
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