PET-CT in Clinical Adult Oncology: I. Hematologic Malignancies

PET-CT is an advanced imaging modality with many oncologic applications, including staging, assessment of response to therapy, restaging and evaluation of suspected recurrence. The goal of this 6-part series of review articles is to provide practical information to providers and imaging professional...

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Main Authors: Ahmed Ebada Salem, Harsh R. Shah, Matthew F. Covington, Bhasker R. Koppula, Gabriel C. Fine, Richard H. Wiggins, John M. Hoffman, Kathryn A. Morton
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/14/23/5941
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author Ahmed Ebada Salem
Harsh R. Shah
Matthew F. Covington
Bhasker R. Koppula
Gabriel C. Fine
Richard H. Wiggins
John M. Hoffman
Kathryn A. Morton
author_facet Ahmed Ebada Salem
Harsh R. Shah
Matthew F. Covington
Bhasker R. Koppula
Gabriel C. Fine
Richard H. Wiggins
John M. Hoffman
Kathryn A. Morton
author_sort Ahmed Ebada Salem
collection DOAJ
description PET-CT is an advanced imaging modality with many oncologic applications, including staging, assessment of response to therapy, restaging and evaluation of suspected recurrence. The goal of this 6-part series of review articles is to provide practical information to providers and imaging professionals regarding the best use of PET-CT for the more common adult malignancies. In the first article of this series, hematologic malignancies are addressed. The classification of these malignancies will be outlined, with the disclaimer that the classification of lymphomas is constantly evolving. Critical applications, potential pitfalls, and nuances of PET-CT imaging in hematologic malignancies and imaging features of the major categories of these tumors are addressed. Issues of clinical importance that must be reported by the imaging professionals are outlined. The focus of this article is on [<sup>18</sup>F] fluorodeoxyglucose (FDG), rather that research tracers or those requiring a local cyclotron. This information will serve as a resource for the appropriate role and limitations of PET-CT in the clinical management of patients with hematological malignancy for health care professionals caring for adult patients with hematologic malignancies. It also serves as a practical guide for imaging providers, including radiologists, nuclear medicine physicians and their trainees.
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spelling doaj.art-ee1ff336dcdc47f4b1b3db7df3ae54112023-11-24T10:41:11ZengMDPI AGCancers2072-66942022-11-011423594110.3390/cancers14235941PET-CT in Clinical Adult Oncology: I. Hematologic MalignanciesAhmed Ebada Salem0Harsh R. Shah1Matthew F. Covington2Bhasker R. Koppula3Gabriel C. Fine4Richard H. Wiggins5John M. Hoffman6Kathryn A. Morton7Department of Radiology and Imaging Sciences, University of Utah, Salt Lake City, UT 84132, USADepartment of Medicine, Division of Hematology, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT 84132, USADepartment of Radiology and Imaging Sciences, University of Utah, Salt Lake City, UT 84132, USADepartment of Radiology and Imaging Sciences, University of Utah, Salt Lake City, UT 84132, USADepartment of Radiology and Imaging Sciences, University of Utah, Salt Lake City, UT 84132, USADepartment of Radiology and Imaging Sciences, University of Utah, Salt Lake City, UT 84132, USADepartment of Radiology and Imaging Sciences, University of Utah, Salt Lake City, UT 84132, USADepartment of Radiology and Imaging Sciences, University of Utah, Salt Lake City, UT 84132, USAPET-CT is an advanced imaging modality with many oncologic applications, including staging, assessment of response to therapy, restaging and evaluation of suspected recurrence. The goal of this 6-part series of review articles is to provide practical information to providers and imaging professionals regarding the best use of PET-CT for the more common adult malignancies. In the first article of this series, hematologic malignancies are addressed. The classification of these malignancies will be outlined, with the disclaimer that the classification of lymphomas is constantly evolving. Critical applications, potential pitfalls, and nuances of PET-CT imaging in hematologic malignancies and imaging features of the major categories of these tumors are addressed. Issues of clinical importance that must be reported by the imaging professionals are outlined. The focus of this article is on [<sup>18</sup>F] fluorodeoxyglucose (FDG), rather that research tracers or those requiring a local cyclotron. This information will serve as a resource for the appropriate role and limitations of PET-CT in the clinical management of patients with hematological malignancy for health care professionals caring for adult patients with hematologic malignancies. It also serves as a practical guide for imaging providers, including radiologists, nuclear medicine physicians and their trainees.https://www.mdpi.com/2072-6694/14/23/5941imagingFDGpositron emission tomographyPETlymphomaleukemia
spellingShingle Ahmed Ebada Salem
Harsh R. Shah
Matthew F. Covington
Bhasker R. Koppula
Gabriel C. Fine
Richard H. Wiggins
John M. Hoffman
Kathryn A. Morton
PET-CT in Clinical Adult Oncology: I. Hematologic Malignancies
Cancers
imaging
FDG
positron emission tomography
PET
lymphoma
leukemia
title PET-CT in Clinical Adult Oncology: I. Hematologic Malignancies
title_full PET-CT in Clinical Adult Oncology: I. Hematologic Malignancies
title_fullStr PET-CT in Clinical Adult Oncology: I. Hematologic Malignancies
title_full_unstemmed PET-CT in Clinical Adult Oncology: I. Hematologic Malignancies
title_short PET-CT in Clinical Adult Oncology: I. Hematologic Malignancies
title_sort pet ct in clinical adult oncology i hematologic malignancies
topic imaging
FDG
positron emission tomography
PET
lymphoma
leukemia
url https://www.mdpi.com/2072-6694/14/23/5941
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AT bhaskerrkoppula petctinclinicaladultoncologyihematologicmalignancies
AT gabrielcfine petctinclinicaladultoncologyihematologicmalignancies
AT richardhwiggins petctinclinicaladultoncologyihematologicmalignancies
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