Improving pharmacometrics analysis efficiency using DataCheQC: An interactive, Shiny‐based app for quality control of pharmacometrics datasets
Abstract DataCheQC is an interactive application based on the R Shiny framework developed for the purposes of performing quality control (QC) checks on pharmacometric datasets, and thereby supporting the implementation of model‐informed drug development. Features include visual inspection of variabl...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2023-10-01
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| Series: | CPT: Pharmacometrics & Systems Pharmacology |
| Online Access: | https://doi.org/10.1002/psp4.13017 |
| _version_ | 1827790984362065920 |
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| author | Or Dotan Andrijana Radivojevic Rajendra Singh |
| author_facet | Or Dotan Andrijana Radivojevic Rajendra Singh |
| author_sort | Or Dotan |
| collection | DOAJ |
| description | Abstract DataCheQC is an interactive application based on the R Shiny framework developed for the purposes of performing quality control (QC) checks on pharmacometric datasets, and thereby supporting the implementation of model‐informed drug development. Features include visual inspection of variables and data entries for errors and/or anomalies, and ensuring structural integrity through comparison with a dataset specification file. The app, which requires no programming knowledge to operate, allows the user to collect all findings into a summary report downloadable directly from the app itself. The source code for the app is freely available on GitHub under an open‐source license (https://github.com/DotanOr/DataCheQC) and can also be accessed online (https://dotanor.shinyapps.io/DataCheQC/). |
| first_indexed | 2024-03-11T17:41:20Z |
| format | Article |
| id | doaj.art-ee243e5ff00d473b914fa83def7967c7 |
| institution | Directory Open Access Journal |
| issn | 2163-8306 |
| language | English |
| last_indexed | 2024-03-11T17:41:20Z |
| publishDate | 2023-10-01 |
| publisher | Wiley |
| record_format | Article |
| series | CPT: Pharmacometrics & Systems Pharmacology |
| spelling | doaj.art-ee243e5ff00d473b914fa83def7967c72023-10-18T10:22:39ZengWileyCPT: Pharmacometrics & Systems Pharmacology2163-83062023-10-0112101375138510.1002/psp4.13017Improving pharmacometrics analysis efficiency using DataCheQC: An interactive, Shiny‐based app for quality control of pharmacometrics datasetsOr Dotan0Andrijana Radivojevic1Rajendra Singh2Teva Pharmaceutical Industries Netanya IsraelintiGROWTH LLC Miami Florida USATeva Pharmaceutical Industries West Chester Pennsylvania USAAbstract DataCheQC is an interactive application based on the R Shiny framework developed for the purposes of performing quality control (QC) checks on pharmacometric datasets, and thereby supporting the implementation of model‐informed drug development. Features include visual inspection of variables and data entries for errors and/or anomalies, and ensuring structural integrity through comparison with a dataset specification file. The app, which requires no programming knowledge to operate, allows the user to collect all findings into a summary report downloadable directly from the app itself. The source code for the app is freely available on GitHub under an open‐source license (https://github.com/DotanOr/DataCheQC) and can also be accessed online (https://dotanor.shinyapps.io/DataCheQC/).https://doi.org/10.1002/psp4.13017 |
| spellingShingle | Or Dotan Andrijana Radivojevic Rajendra Singh Improving pharmacometrics analysis efficiency using DataCheQC: An interactive, Shiny‐based app for quality control of pharmacometrics datasets CPT: Pharmacometrics & Systems Pharmacology |
| title | Improving pharmacometrics analysis efficiency using DataCheQC: An interactive, Shiny‐based app for quality control of pharmacometrics datasets |
| title_full | Improving pharmacometrics analysis efficiency using DataCheQC: An interactive, Shiny‐based app for quality control of pharmacometrics datasets |
| title_fullStr | Improving pharmacometrics analysis efficiency using DataCheQC: An interactive, Shiny‐based app for quality control of pharmacometrics datasets |
| title_full_unstemmed | Improving pharmacometrics analysis efficiency using DataCheQC: An interactive, Shiny‐based app for quality control of pharmacometrics datasets |
| title_short | Improving pharmacometrics analysis efficiency using DataCheQC: An interactive, Shiny‐based app for quality control of pharmacometrics datasets |
| title_sort | improving pharmacometrics analysis efficiency using datacheqc an interactive shiny based app for quality control of pharmacometrics datasets |
| url | https://doi.org/10.1002/psp4.13017 |
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