Data for homogeneous thermofluorimetric assays for ethanolamine using aptamers and a PCR instrument

The data presented in this article describe the quantitative detection of small molecules e.g. ethanolamine through the shifts in the melting temperatures of aptamer beacons presented in the research article entitled “An aptamer based thermofluorimetric assay for ethanolamine” [1]. The data include...

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Main Authors: Mostafa Mahmoud, Stefan Laufer, Hans-Peter Deigner
Format: Article
Language:English
Published: Elsevier 2019-06-01
Series:Data in Brief
Online Access:http://www.sciencedirect.com/science/article/pii/S2352340919302975
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author Mostafa Mahmoud
Stefan Laufer
Hans-Peter Deigner
author_facet Mostafa Mahmoud
Stefan Laufer
Hans-Peter Deigner
author_sort Mostafa Mahmoud
collection DOAJ
description The data presented in this article describe the quantitative detection of small molecules e.g. ethanolamine through the shifts in the melting temperatures of aptamer beacons presented in the research article entitled “An aptamer based thermofluorimetric assay for ethanolamine” [1]. The data include prediction and optimization of the folding structure of the aptamers. Moreover, the data from using intercalating dyes such as SYBR green is included for comparison. The presented data could be used for the design of other small molecules sensing platforms using aptamers.
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spelling doaj.art-ee28dbfa0a184903a94f1b5c964e02ed2022-12-22T03:46:51ZengElsevierData in Brief2352-34092019-06-0124Data for homogeneous thermofluorimetric assays for ethanolamine using aptamers and a PCR instrumentMostafa Mahmoud0Stefan Laufer1Hans-Peter Deigner2Furtwangen University, Institute of Precision Medicine, Jakob-Kienzle-Straße 17, 78054, Villingen-Schwenningen, Germany; Department of Pharmaceutical and Medicinal Chemistry, Institute of Pharmaceutical Sciences, Eberhard Karls Universität Tübingen, Auf der Morgenstelle 8, 72076 Tübingen, GermanyDepartment of Pharmaceutical and Medicinal Chemistry, Institute of Pharmaceutical Sciences, Eberhard Karls Universität Tübingen, Auf der Morgenstelle 8, 72076 Tübingen, GermanyFurtwangen University, Institute of Precision Medicine, Jakob-Kienzle-Straße 17, 78054, Villingen-Schwenningen, Germany; Fraunhofer Institute IZI, Leipzig, EXIM Department, Schillingallee 68, D-18057, Rostock, Germany; Corresponding author. Furtwangen University, Institute of Precision Medicine, Jakob-Kienzle-Straße 17, 78054, Villingen-Schwenningen, Germany.The data presented in this article describe the quantitative detection of small molecules e.g. ethanolamine through the shifts in the melting temperatures of aptamer beacons presented in the research article entitled “An aptamer based thermofluorimetric assay for ethanolamine” [1]. The data include prediction and optimization of the folding structure of the aptamers. Moreover, the data from using intercalating dyes such as SYBR green is included for comparison. The presented data could be used for the design of other small molecules sensing platforms using aptamers.http://www.sciencedirect.com/science/article/pii/S2352340919302975
spellingShingle Mostafa Mahmoud
Stefan Laufer
Hans-Peter Deigner
Data for homogeneous thermofluorimetric assays for ethanolamine using aptamers and a PCR instrument
Data in Brief
title Data for homogeneous thermofluorimetric assays for ethanolamine using aptamers and a PCR instrument
title_full Data for homogeneous thermofluorimetric assays for ethanolamine using aptamers and a PCR instrument
title_fullStr Data for homogeneous thermofluorimetric assays for ethanolamine using aptamers and a PCR instrument
title_full_unstemmed Data for homogeneous thermofluorimetric assays for ethanolamine using aptamers and a PCR instrument
title_short Data for homogeneous thermofluorimetric assays for ethanolamine using aptamers and a PCR instrument
title_sort data for homogeneous thermofluorimetric assays for ethanolamine using aptamers and a pcr instrument
url http://www.sciencedirect.com/science/article/pii/S2352340919302975
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