Cell-Free DNA: Hope and Potential Application in Cancer
Cell-free DNA (cfDNA) is easily accessible in peripheral blood and can be used as biomarkers for cancer diagnostics, prognostics, and therapeutics. The applications of cfDNA in various areas of cancer management are attracting attention. In this review article, we discuss the potential relevance of...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2021-02-01
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| Series: | Frontiers in Cell and Developmental Biology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fcell.2021.639233/full |
| _version_ | 1819050648293867520 |
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| author | Yan-yan Yan Yan-yan Yan Qiao-ru Guo Qiao-ru Guo Feng-hua Wang Rameshwar Adhikari Zhuang-yan Zhu Hai-yan Zhang Wen-min Zhou Hua Yu Jing-quan Li Jian-ye Zhang Jian-ye Zhang Jian-ye Zhang |
| author_facet | Yan-yan Yan Yan-yan Yan Qiao-ru Guo Qiao-ru Guo Feng-hua Wang Rameshwar Adhikari Zhuang-yan Zhu Hai-yan Zhang Wen-min Zhou Hua Yu Jing-quan Li Jian-ye Zhang Jian-ye Zhang Jian-ye Zhang |
| author_sort | Yan-yan Yan |
| collection | DOAJ |
| description | Cell-free DNA (cfDNA) is easily accessible in peripheral blood and can be used as biomarkers for cancer diagnostics, prognostics, and therapeutics. The applications of cfDNA in various areas of cancer management are attracting attention. In this review article, we discuss the potential relevance of using cfDNA analysis in clinical oncology, particularly in cancer screening, early diagnosis, therapeutic evaluation, monitoring disease progression; and determining disease prognosis. |
| first_indexed | 2024-12-21T11:51:23Z |
| format | Article |
| id | doaj.art-ee29af4cbd1a4acbbf3edea1d53cf5f4 |
| institution | Directory Open Access Journal |
| issn | 2296-634X |
| language | English |
| last_indexed | 2024-12-21T11:51:23Z |
| publishDate | 2021-02-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Cell and Developmental Biology |
| spelling | doaj.art-ee29af4cbd1a4acbbf3edea1d53cf5f42022-12-21T19:05:02ZengFrontiers Media S.A.Frontiers in Cell and Developmental Biology2296-634X2021-02-01910.3389/fcell.2021.639233639233Cell-Free DNA: Hope and Potential Application in CancerYan-yan Yan0Yan-yan Yan1Qiao-ru Guo2Qiao-ru Guo3Feng-hua Wang4Rameshwar Adhikari5Zhuang-yan Zhu6Hai-yan Zhang7Wen-min Zhou8Hua Yu9Jing-quan Li10Jian-ye Zhang11Jian-ye Zhang12Jian-ye Zhang13School of Medicine, Shanxi Datong University, Datong, ChinaKey Laboratory of Molecular Target and Clinical Pharmacology and the State Key Laboratory of Respiratory Disease, School of Pharmaceutical Sciences and the Fifth Affiliated Hospital, Guangzhou Medical University, Guangzhou, ChinaKey Laboratory of Molecular Target and Clinical Pharmacology and the State Key Laboratory of Respiratory Disease, School of Pharmaceutical Sciences and the Fifth Affiliated Hospital, Guangzhou Medical University, Guangzhou, ChinaThe First Affiliated Hospital, Hainan Medical University, Haikou, ChinaGuangzhou Institute of Pediatrics/Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, ChinaResearch Centre for Applied Science and Technology, Tribhuvan University, Kirtipur, NepalSchool of Medicine, Shanxi Datong University, Datong, ChinaSchool of Medicine, Shanxi Datong University, Datong, ChinaKey Laboratory of Molecular Target and Clinical Pharmacology and the State Key Laboratory of Respiratory Disease, School of Pharmaceutical Sciences and the Fifth Affiliated Hospital, Guangzhou Medical University, Guangzhou, ChinaState Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, Avenida da Universidade, Taipa, ChinaThe First Affiliated Hospital, Hainan Medical University, Haikou, ChinaSchool of Medicine, Shanxi Datong University, Datong, ChinaKey Laboratory of Molecular Target and Clinical Pharmacology and the State Key Laboratory of Respiratory Disease, School of Pharmaceutical Sciences and the Fifth Affiliated Hospital, Guangzhou Medical University, Guangzhou, ChinaThe First Affiliated Hospital, Hainan Medical University, Haikou, ChinaCell-free DNA (cfDNA) is easily accessible in peripheral blood and can be used as biomarkers for cancer diagnostics, prognostics, and therapeutics. The applications of cfDNA in various areas of cancer management are attracting attention. In this review article, we discuss the potential relevance of using cfDNA analysis in clinical oncology, particularly in cancer screening, early diagnosis, therapeutic evaluation, monitoring disease progression; and determining disease prognosis.https://www.frontiersin.org/articles/10.3389/fcell.2021.639233/fullcell-free DNA (cfDNA)cancerdiagnosistherapeutic effect evaluationliquid biopsy |
| spellingShingle | Yan-yan Yan Yan-yan Yan Qiao-ru Guo Qiao-ru Guo Feng-hua Wang Rameshwar Adhikari Zhuang-yan Zhu Hai-yan Zhang Wen-min Zhou Hua Yu Jing-quan Li Jian-ye Zhang Jian-ye Zhang Jian-ye Zhang Cell-Free DNA: Hope and Potential Application in Cancer Frontiers in Cell and Developmental Biology cell-free DNA (cfDNA) cancer diagnosis therapeutic effect evaluation liquid biopsy |
| title | Cell-Free DNA: Hope and Potential Application in Cancer |
| title_full | Cell-Free DNA: Hope and Potential Application in Cancer |
| title_fullStr | Cell-Free DNA: Hope and Potential Application in Cancer |
| title_full_unstemmed | Cell-Free DNA: Hope and Potential Application in Cancer |
| title_short | Cell-Free DNA: Hope and Potential Application in Cancer |
| title_sort | cell free dna hope and potential application in cancer |
| topic | cell-free DNA (cfDNA) cancer diagnosis therapeutic effect evaluation liquid biopsy |
| url | https://www.frontiersin.org/articles/10.3389/fcell.2021.639233/full |
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